{"id":"W2000825465","doi":"10.1074/jbc.m105676200","title":"Co-localization of Leukotriene A4Hydrolase with 5-Lipoxygenase in Nuclei of Alveolar Macrophages and Rat Basophilic Leukemia Cells but Not Neutrophils","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Leukotriene B4; Leukotriene; Cytoplasm; Arachidonate 5-lipoxygenase; Leukotriene C4; Cytosol; Leukotriene D4; Lipoxygenase; Arachidonic acid; Chemistry; Biochemistry; Molecular biology; Biology; Enzyme; Immunology; Inflammation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003892356,0.000157114,0.0004671184,0.00007996723,0.00004254683,0.000006011307,0.0001576336,0.0003376294,0.0001937733],"category_scores_gemma":[0.0001251437,0.0001062477,0.00009107599,0.000151409,0.0003560194,0.00009488773,0.00002895256,0.0003091344,0.000003776506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005704294,"about_ca_system_score_gemma":0.00009849822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001438073,"about_ca_topic_score_gemma":5.095087e-7,"domain_scores_codex":[0.9987559,0.0001450132,0.0007015586,0.000146728,0.00005970966,0.0001910664],"domain_scores_gemma":[0.9989145,0.0001544091,0.0006166101,0.0001414119,0.0001402752,0.000032739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003204989,0.000109144,0.00334584,0.00005740156,0.00005952232,0.00007527563,0.00007156545,0.0002760936,0.992065,0.000005651695,0.00004556304,0.0006839919],"study_design_scores_gemma":[0.002168681,0.000567911,0.004406513,0.00009702427,0.00002862561,0.0004648216,0.0001231908,0.00002670671,0.9910172,0.0000310831,0.0009575952,0.0001106589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974576,0.002106254,0.0001039091,0.00009537995,0.00004685991,0.00007788072,0.0000109897,0.000005765128,0.00009538],"genre_scores_gemma":[0.9979196,0.001816877,0.00004756086,0.00004565386,0.00003266416,0.000001436899,0.00002298532,0.000007408764,0.0001058012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001060672,"threshold_uncertainty_score":0.4332654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007509562111617,"score_gpt":0.2190076900331648,"score_spread":0.2089325944120486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}