{"id":"W2000853346","doi":"10.1002/cncr.23864","title":"Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone‐refractory prostate cancer","year":2008,"lang":"en","type":"article","venue":"Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":245,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Victoria Hospital; London Health Sciences Centre","funders":"National Cancer Institute","keywords":"Medicine; Clinical endpoint; Placebo; Urology; Peripheral edema; Prostate cancer; Internal medicine; Doubling time; Prostate; Randomized controlled trial; Prostate-specific antigen; Adverse effect; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002893112,0.0002341424,0.001595985,0.0002053956,0.00005440707,0.000006134495,0.0000700939,0.00006099711,0.0003284448],"category_scores_gemma":[0.00007442997,0.0001343769,0.0002153548,0.000275555,0.0004069721,0.0001147918,0.00001722074,0.0002141437,0.000004453372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003282764,"about_ca_system_score_gemma":0.0008364973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004708775,"about_ca_topic_score_gemma":0.00004890576,"domain_scores_codex":[0.9979785,0.00014674,0.0005926614,0.0002943064,0.0006138957,0.0003738596],"domain_scores_gemma":[0.9988961,0.0001794952,0.0002707373,0.0002259334,0.0002588809,0.0001688908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9688662,0.002911035,0.02139479,0.00006353233,0.0007167151,0.00008248414,0.0006885467,0.00001447511,0.0003263604,0.000003250315,0.0005906559,0.004342003],"study_design_scores_gemma":[0.9902959,0.002890114,0.004880921,0.0001552776,0.0003987081,0.000001340031,0.00004595384,0.00006809043,0.0007134486,0.000007172665,0.0003952976,0.0001477411],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825575,0.007553434,0.000007665865,0.0002444485,0.0001837451,0.008780234,0.000136532,0.00001767196,0.0005187364],"genre_scores_gemma":[0.9830676,0.01146548,0.00006741119,0.00008937063,0.0001187548,0.003079041,0.00007175814,0.00003471631,0.002005875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02142978,"threshold_uncertainty_score":0.5479731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01803086153307878,"score_gpt":0.3255728464527888,"score_spread":0.3075419849197101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}