{"id":"W2000869009","doi":"10.1007/s00467-007-0444-z","title":"Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop","year":2007,"lang":"en","type":"article","venue":"Pediatric Nephrology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôtel-Dieu de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Autocrine signalling; Transfection; Apoptosis; Cell biology; Cell growth; Biology; Embryonic stem cell; Paracrine signalling; Molecular biology; Cell culture; Downregulation and upregulation; Gene; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002945628,0.0003787482,0.0002937787,0.0005612168,0.0004032956,0.0009744546,0.0004768244,0.00028255,0.002087148],"category_scores_gemma":[0.0003769507,0.0003211088,0.0002483994,0.0002498733,0.0004882719,0.000994912,0.0008492395,0.0006490499,0.0003667243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007056712,"about_ca_system_score_gemma":0.0004067072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004625507,"about_ca_topic_score_gemma":0.001273282,"domain_scores_codex":[0.9996129,0.00008695236,0.00001663382,0.00005317203,0.0001478403,0.00008250357],"domain_scores_gemma":[0.9996377,0.0000842751,0.00006743803,0.00003176561,0.00008912251,0.00008961564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005848735,0.0000564721,0.003180834,0.00005222124,0.00002234471,0.0004631284,0.00008661893,0.0002446203,0.9787133,0.003428008,0.0002833821,0.01288418],"study_design_scores_gemma":[0.0001387378,0.0003969453,0.03030114,0.00001991017,0.00005229671,0.001935647,0.0004355608,0.00377629,0.9498194,0.002233468,0.01087115,0.00001944375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9674903,0.007686403,0.01111283,0.0006394752,0.0001314988,0.00003433,0.0001678968,0.0002900421,0.0124473],"genre_scores_gemma":[0.9893427,0.001452685,0.003182562,0.00007090005,0.00004205014,0.00003330484,0.0001056909,0.0000289347,0.005741186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002087148,"threshold_uncertainty_score":0.006982207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003153698689522817,"score_gpt":0.2091798084541969,"score_spread":0.2060261097646741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}