{"id":"W2000917831","doi":"10.1111/j.1471-4159.2004.02841.x","title":"Insulin exerts neuroprotection by counteracting the decrease in cell‐surface GABA<sub>A</sub> receptors following oxygen–glucose deprivation in cultured cortical neurons","year":2004,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Institute for Biological Sciences; Hospital for Sick Children; University of Toronto","funders":"Heart and Stroke Foundation of British Columbia and Yukon; University of British Columbia; Heart and Stroke Foundation of Canada; Howard Hughes Medical Institute","keywords":"Neuroprotection; Receptor; Neuroscience; Oxygen; Cortical neurons; Chemistry; Internal medicine; Endocrinology; Biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006523439,0.0002926711,0.0003182332,0.0001687726,0.0003300775,0.0001541637,0.0007611097,0.0001270651,0.0000118826],"category_scores_gemma":[0.005201713,0.0002419713,0.0001801941,0.001262319,0.0001887687,0.0006644242,0.0001569887,0.002388157,0.0000143315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001813106,"about_ca_system_score_gemma":0.0002996299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007826915,"about_ca_topic_score_gemma":0.000003921094,"domain_scores_codex":[0.9964085,0.0005962078,0.0008737557,0.0006117278,0.0008879265,0.0006218836],"domain_scores_gemma":[0.9981136,0.0007259783,0.000490948,0.0002779233,0.00008721418,0.0003043834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003042823,0.0004917996,0.0007151256,0.00001847405,0.000001596227,0.001637326,0.0001645267,0.002327358,0.9939161,6.440114e-7,0.0002815411,0.0001412214],"study_design_scores_gemma":[0.001845293,0.0002064309,0.002723793,0.00006584836,0.00001361214,0.000741213,0.00008268032,0.0004842981,0.9933765,0.00003647319,0.0002397061,0.0001841363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972006,0.00007782887,0.00005391856,0.001395376,0.0008264636,0.0003242914,0.000004676198,0.00002558433,0.000091257],"genre_scores_gemma":[0.9974633,0.0006358704,0.0000217791,0.001704398,0.00009944663,0.00001082352,7.187914e-7,0.00004011229,0.000023504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004549369,"threshold_uncertainty_score":0.9999134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02102666575931729,"score_gpt":0.2921114349199074,"score_spread":0.2710847691605902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}