{"id":"W2000930832","doi":"10.1016/j.bmc.2008.12.009","title":"Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp.","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Phoma; Aspergillus fumigatus; Candida albicans; Chemistry; Fungi imperfecti; Stereochemistry; Trichophyton; Microbiology; Toxicity; Antifungal; Biological activity; Aspergillus; Fungus; Biochemistry; Biology; In vitro; Botany; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008369743,0.0002663792,0.0006410526,0.00002648477,0.00009675308,0.000005010257,0.0001277314,0.0003653994,0.0009061427],"category_scores_gemma":[0.0007314687,0.0002002094,0.0001130944,0.0002014989,0.0006452516,0.00005976012,0.00006749047,0.0004447477,0.00000596568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008799113,"about_ca_system_score_gemma":0.0002253422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001241374,"about_ca_topic_score_gemma":0.00001437179,"domain_scores_codex":[0.9983522,0.00004135703,0.0003824203,0.0005292046,0.0004021849,0.0002926324],"domain_scores_gemma":[0.9987787,0.0002104215,0.0001597781,0.0004373313,0.0001171982,0.0002965615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005450209,0.0001005679,0.3938192,0.00007960738,0.00004590899,0.00005970377,0.0001357328,1.76137e-8,0.6044513,0.000001930446,0.0002642221,0.000496778],"study_design_scores_gemma":[0.0009485448,0.0001214773,0.5685863,0.0001021945,0.00006506288,0.0001748319,0.00009974268,0.00002319044,0.4296002,0.00006383114,0.000106917,0.000107619],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969955,0.00163153,0.0003638788,0.000393971,0.00006525162,0.0001667156,0.00007894816,0.00006418521,0.0002400057],"genre_scores_gemma":[0.998193,0.0003496775,0.0006476296,0.0001674389,0.0004022124,0.000002964444,0.00005942726,0.00001915946,0.0001584668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1748511,"threshold_uncertainty_score":0.9921627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02099567120928451,"score_gpt":0.248641421548801,"score_spread":0.2276457503395165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}