{"id":"W2000930832","doi":"10.1016/j.bmc.2008.12.009","title":"Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp.","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Phoma; Aspergillus fumigatus; Candida albicans; Chemistry; Fungi imperfecti; Stereochemistry; Trichophyton; Microbiology; Toxicity; Antifungal; Biological activity; Aspergillus; Fungus; Biochemistry; Biology; In vitro; Botany; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005638023,0.0002509144,0.0001002929,0.0002054272,0.0001360714,0.0001480556,0.0001143589,0.0001739648,0.0005411101],"category_scores_gemma":[0.0001079799,0.00005763307,0.000136424,0.0001672005,0.0001866508,0.0001793914,0.0001239371,0.0003375166,0.0001386278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001195279,"about_ca_system_score_gemma":0.0001874616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001199085,"about_ca_topic_score_gemma":0.0008549507,"domain_scores_codex":[0.9999777,0.000003295292,0.000002068424,0.000006446628,0.000004853337,0.000005655272],"domain_scores_gemma":[0.9999229,0.00002315564,0.0000167083,0.000005717393,0.00001107451,0.00002043205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001229523,0.00002044036,0.0005983922,0.00003002104,0.000002844622,0.0001646886,0.00001243889,0.0001099472,0.9957694,0.00002484421,0.00001522574,0.003128872],"study_design_scores_gemma":[0.00006120592,0.001292404,0.03973997,0.00001867998,0.00004033192,0.00190885,0.0001084554,0.0009335625,0.9527007,0.000103124,0.003080846,0.00001186571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966092,0.001109863,0.0009957764,0.0000640607,0.000006174265,0.00002632579,0.000416759,0.000005500347,0.0007663221],"genre_scores_gemma":[0.9957865,0.0007906716,0.00165303,0.00003571832,0.00001079941,0.00001312911,0.0008977337,0.000003561259,0.0008088836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001199085,"threshold_uncertainty_score":0.002384186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02099567120928451,"score_gpt":0.248641421548801,"score_spread":0.2276457503395165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}