{"id":"W2000962968","doi":"10.1021/bi015967+","title":"Calnexin Deficiency and Endoplasmic Reticulum Stress-Induced Apoptosis","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Calnexin; Endoplasmic reticulum; Unfolded protein response; Apoptosis; Cell biology; Cleavage (geology); Immunoprecipitation; Biology; Thapsigargin; Calreticulin; Chemistry; Biochemistry; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001139526,0.0002921467,0.0002535341,0.0001972303,0.0001186821,0.0003336256,0.0001213125,0.0002873164,0.0008274331],"category_scores_gemma":[0.0001753614,0.00008982115,0.0001343904,0.0001469942,0.0001638809,0.0002914223,0.0001934312,0.0003598174,0.0001864022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002051266,"about_ca_system_score_gemma":0.00008670892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001552082,"about_ca_topic_score_gemma":0.0002154667,"domain_scores_codex":[0.9998945,0.00002478757,0.00001484001,0.00002052256,0.00002392886,0.00002132681],"domain_scores_gemma":[0.9998486,0.00003101536,0.000052843,0.00002167721,0.00001647369,0.00002944041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003520267,0.00004821067,0.0007221941,0.00005207346,0.000009865783,0.0004919955,0.00001686153,0.00006436804,0.9963929,0.0001944004,0.00003314197,0.001621952],"study_design_scores_gemma":[0.00007886731,0.0007412312,0.01537407,0.00001394201,0.00002986958,0.003509797,0.00007598959,0.0009171958,0.974727,0.0003477249,0.004177089,0.000007273844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963084,0.002014859,0.0008887738,0.0000680471,0.00001960893,0.00001129009,0.00008472557,0.00002097973,0.0005832432],"genre_scores_gemma":[0.9965572,0.001520112,0.0006118658,0.00002808466,0.00000631651,0.00001230743,0.0002358402,0.000007191988,0.001021106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008274331,"threshold_uncertainty_score":0.00276804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00987339689548061,"score_gpt":0.2155480755945976,"score_spread":0.205674678699117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}