{"id":"W2000976083","doi":"10.1161/circulationaha.107.739938","title":"Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways","year":2008,"lang":"en","type":"article","venue":"Circulation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":1046,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Medicine; Glucagon-like peptide-1; Internal medicine; Glucagon-like peptide 1 receptor; Vasodilation; Endocrinology; Nitric oxide; Agonist; Receptor; Dipeptidyl peptidase-4; Pharmacology; Nitric oxide synthase; Incretin; Type 2 diabetes; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003520289,0.0004342528,0.0002686329,0.0002031779,0.00010283,0.0002344479,0.0002682863,0.0002798132,0.001877567],"category_scores_gemma":[0.0001814442,0.0001364236,0.0004144737,0.00009073583,0.0002548117,0.0002633254,0.0001997754,0.0007551321,0.0003600332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001578298,"about_ca_system_score_gemma":0.0001456863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007857564,"about_ca_topic_score_gemma":0.000112229,"domain_scores_codex":[0.9998585,0.0000318546,0.00001028336,0.00003021155,0.00003406015,0.00003511383],"domain_scores_gemma":[0.9998409,0.00002762746,0.00006819816,0.00001340946,0.00001764292,0.00003222621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004453609,0.00005591551,0.0004099181,0.0001272205,0.00001819066,0.000136003,0.0000135063,0.00004997924,0.9936784,0.0002228011,0.0001175963,0.004725045],"study_design_scores_gemma":[0.0004657844,0.004603917,0.08649341,0.0001049559,0.0002162018,0.001942681,0.0001180118,0.001667446,0.8918257,0.0008995649,0.01162155,0.00004069267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736448,0.01414698,0.006442134,0.0006147154,0.0002140267,0.00006931751,0.0004706011,0.0001469792,0.004250359],"genre_scores_gemma":[0.9833542,0.008506333,0.003885433,0.0004629479,0.0002087956,0.000119701,0.0006184645,0.00002521746,0.002818899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001877567,"threshold_uncertainty_score":0.006281137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03600998559058563,"score_gpt":0.2445760992201535,"score_spread":0.2085661136295679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}