{"id":"W2000993433","doi":"10.1002/jbm.a.31019","title":"Enhanced antigen‐specific primary CD4<sup>+</sup> and CD8<sup>+</sup> responses by codelivery of ovalbumin and toll‐like receptor ligand monophosphoryl lipid A in poly(<scp>D,L</scp>‐lactic‐<i>co</i>‐glycolic acid) nanoparticles","year":2006,"lang":"en","type":"article","venue":"Journal of Biomedical Materials Research Part A","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"T cell; CD8; Ovalbumin; Antigen; Cytotoxic T cell; Adoptive cell transfer; Antigen-presenting cell; Molecular biology; Biology; Materials science; Immune system; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005314431,0.0004343976,0.001322049,0.0009747213,0.0003502845,0.0001690525,0.0005261817,0.0006465421,0.0003518662],"category_scores_gemma":[0.001133502,0.0003553647,0.0001492716,0.0006217127,0.002368926,0.0004408856,0.0002629406,0.0008260426,0.00006718274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000146719,"about_ca_system_score_gemma":0.0005478212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001583008,"about_ca_topic_score_gemma":0.000002826988,"domain_scores_codex":[0.9929954,0.002853303,0.001902724,0.0005345406,0.0005394359,0.001174573],"domain_scores_gemma":[0.9958915,0.002571116,0.000585829,0.0004217551,0.000347182,0.000182621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01153073,0.0008814975,0.0004152409,0.0001536709,0.0002334574,0.00006370444,0.001633417,0.000001000676,0.9489041,0.00001522782,0.0324038,0.003764183],"study_design_scores_gemma":[0.004290563,0.002099501,0.002500877,0.0005039789,0.0000195854,0.0003186429,0.001308333,0.000003270077,0.8413925,0.00005490136,0.1473319,0.0001759579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9354484,0.06278834,0.00002011181,0.0005331687,0.0003375404,0.000527706,0.0002801015,0.00002351798,0.00004108687],"genre_scores_gemma":[0.9703317,0.02765182,0.0001952246,0.0001092086,0.0002196033,0.00004371363,0.00007394525,0.00005672901,0.001318105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1149281,"threshold_uncertainty_score":0.9998899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01855563912634619,"score_gpt":0.2814379021716458,"score_spread":0.2628822630452997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}