{"id":"W2001010186","doi":"10.1002/art.27382","title":"Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis","year":2010,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; Canadian Institutes of Health Research; Versus Arthritis","keywords":"CTGF; Fibrosis; Connective tissue; Growth factor; Fibroblast; Biology; Pulmonary fibrosis; Matricellular protein; Transforming growth factor; Cancer research; Extracellular matrix; Pathology; Cell biology; Medicine; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002999667,0.0005210268,0.0002092732,0.0002591746,0.0001434882,0.0002381922,0.0001267594,0.0002597532,0.001345108],"category_scores_gemma":[0.0001391256,0.0001564211,0.0002820497,0.0001474145,0.0002307275,0.0001463531,0.0001656367,0.0004547319,0.0005253014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000227717,"about_ca_system_score_gemma":0.0001843571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003863906,"about_ca_topic_score_gemma":0.0007926826,"domain_scores_codex":[0.9997819,0.00004408768,0.000022153,0.00005004783,0.00005555816,0.00004624515],"domain_scores_gemma":[0.9998047,0.00005529718,0.00005017801,0.00002630769,0.00001418644,0.00004941477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009654771,0.00002385586,0.00008394156,0.00001971733,0.000002151514,0.00003792864,0.000008098431,0.00001710396,0.9992076,0.00002871472,0.00002040508,0.0004539539],"study_design_scores_gemma":[0.00004267705,0.0006197686,0.002669518,0.000009960697,0.00001748422,0.0003398475,0.00001544377,0.0005001403,0.9942805,0.00002471223,0.001476829,0.000003143999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903708,0.002671946,0.00397647,0.0001033624,0.00005642757,0.00005905297,0.00040809,0.000134267,0.002219571],"genre_scores_gemma":[0.9917547,0.001261334,0.003585675,0.00005102247,0.0000199394,0.00006188522,0.0005392953,0.00002277794,0.002703436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001345108,"threshold_uncertainty_score":0.004499793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007938807278344685,"score_gpt":0.2607651717609503,"score_spread":0.2528263644826056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}