{"id":"W2001015151","doi":"10.1097/cmr.0b013e3282f702cf","title":"Clinical phase I intratumoral administration of two recombinant ALVAC canarypox viruses expressing human granulocyte-macrophage colony-stimulating factor or interleukin-2: the transgene determines the composition of the inflammatory infiltrate","year":2008,"lang":"en","type":"article","venue":"Melanoma Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Immunology; Granulocyte macrophage colony-stimulating factor; Medicine; Immunotherapy; Cytokine; Biology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001790259,0.0002160805,0.0004423221,0.0001175846,0.001447101,0.00003508689,0.0008341753,0.0001872743,0.0001975158],"category_scores_gemma":[0.0002451539,0.000106916,0.0002241587,0.0003167158,0.002434091,0.0001450393,0.0001275679,0.0009368458,0.000008030328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000542312,"about_ca_system_score_gemma":0.0004850191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005276743,"about_ca_topic_score_gemma":0.0003854232,"domain_scores_codex":[0.9939749,0.004073051,0.001046041,0.0002677934,0.0001936919,0.000444552],"domain_scores_gemma":[0.9966643,0.001991997,0.0003944593,0.0006600861,0.0002656572,0.00002352434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005459526,0.0003787237,0.011177,0.00003714318,0.0001500373,0.00003265618,0.00229896,0.000009284154,0.9760265,0.00006893268,0.0001778528,0.004183318],"study_design_scores_gemma":[0.003583966,0.002218785,0.07196114,0.0001840054,0.00002881658,0.0002474733,0.0004602156,0.00005974199,0.9196207,0.00003478075,0.001459883,0.0001405051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970349,0.001249005,0.00003576975,0.0002188582,0.000534362,0.0008001432,0.00004461695,0.00001911917,0.00006321655],"genre_scores_gemma":[0.9991112,0.000125003,0.00002549087,0.00005247344,0.00006237214,0.00005667499,0.00002464778,0.00002422263,0.0005178754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06078414,"threshold_uncertainty_score":0.9998529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1494183738160601,"score_gpt":0.4325648940757927,"score_spread":0.2831465202597326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}