{"id":"W2001020014","doi":"10.1016/j.neurobiolaging.2009.04.021","title":"Apolipoprotein E: Implications for AD neurobiology, epidemiology and risk assessment","year":2009,"lang":"en","type":"review","venue":"Neurobiology of Aging","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Apolipoprotein E; Epidemiology; Disease; Allele; Risk factor; Medicine; Alzheimer's disease; Psychology; Intervention (counseling); Neuroscience; Psychiatry; Genetics; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005865314,0.0004684074,0.002680649,0.0003275202,0.0001757929,0.000005166407,0.0002079207,0.0004372543,0.00001176824],"category_scores_gemma":[0.0004688598,0.0003467554,0.0005189824,0.0002035582,0.0004881257,0.00003347954,0.0001322955,0.0006503297,0.00000857702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005739147,"about_ca_system_score_gemma":0.0005091474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003171914,"about_ca_topic_score_gemma":0.000004413416,"domain_scores_codex":[0.9966075,0.0009169533,0.0008746649,0.0008751243,0.00004139925,0.0006843759],"domain_scores_gemma":[0.9961451,0.002001176,0.0007431554,0.0006571603,0.000159831,0.0002936298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005841215,0.0004104552,0.01160369,0.006041977,0.007380097,0.00001018184,0.000006345177,5.192124e-7,0.000005953382,0.0009132887,0.0009968268,0.9725723],"study_design_scores_gemma":[0.003926198,0.006480751,0.1373017,0.006035603,0.02443459,0.001026373,0.000007616164,0.00001559161,0.00001670335,0.004331266,0.815444,0.0009796496],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006118816,0.9941289,0.00006996847,0.00134053,0.00009286917,0.002824182,0.0007324129,0.00005985148,0.0001393454],"genre_scores_gemma":[0.0005207033,0.994958,0.002408408,0.0002589025,0.0001083073,0.0005306655,0.001133333,0.00005026581,0.00003145254],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9715926,"threshold_uncertainty_score":0.9998984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1177477273236576,"score_gpt":0.4598527859162429,"score_spread":0.3421050585925853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}