{"id":"W2001054548","doi":"10.1371/journal.pone.0045595","title":"Humanization and Characterization of an Anti-Ricin Neutralization Monoclonal Antibody","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Ricin; Monoclonal antibody; Antibody; Recombinant DNA; Immunoglobulin light chain; Molecular biology; Lethal dose; Virology; Biology; Neutralization; Chemistry; Biochemistry; Gene; Immunology; Toxin; Toxicology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000322825,0.0003884081,0.0002063046,0.0002942143,0.0001209555,0.0003119388,0.0003519882,0.0003613426,0.001134058],"category_scores_gemma":[0.0003233468,0.0001222132,0.0003350581,0.0001933942,0.0001165871,0.000139255,0.0001929851,0.0006096947,0.0009194574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003233619,"about_ca_system_score_gemma":0.0001678938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005747273,"about_ca_topic_score_gemma":0.0004655169,"domain_scores_codex":[0.9997961,0.00003773023,0.00001760908,0.00003724207,0.00006766286,0.00004361391],"domain_scores_gemma":[0.9998727,0.0000193381,0.00001524188,0.00001938293,0.00004329058,0.00003001492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003907683,0.00008953003,0.0001431935,0.00003158785,0.00000770919,0.00006728435,0.00002134339,0.0001546408,0.9961325,0.00009142855,0.0001208304,0.003100955],"study_design_scores_gemma":[0.00004840417,0.00118096,0.00366026,0.00001803114,0.00003839349,0.0007227582,0.00002846797,0.001747453,0.9653506,0.0000922656,0.0271023,0.00001006633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9536313,0.00350746,0.03364629,0.0003803476,0.0001090446,0.0008678138,0.001396664,0.0001545613,0.00630655],"genre_scores_gemma":[0.9653458,0.002206343,0.01810776,0.0004731655,0.00005807713,0.0002669923,0.004826671,0.00005624618,0.008658945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134058,"threshold_uncertainty_score":0.003793836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0265221886116067,"score_gpt":0.2359054130339957,"score_spread":0.209383224422389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}