{"id":"W2001067434","doi":"10.1002/adfm.201402408","title":"Intracellular Microenvironment‐Responsive Dendrimer‐Like Mesoporous Nanohybrids for Traceable, Effective, and Safe Gene Delivery","year":2014,"lang":"en","type":"article","venue":"Advanced Functional Materials","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Australian Research Council","keywords":"Nanocarriers; Gene delivery; Intracellular; Dendrimer; Materials science; Gene silencing; Mesoporous silica; Nanotechnology; Biophysics; Cytotoxicity; Drug delivery; Genetic enhancement; Mesoporous material; Chemistry; Gene; Biochemistry; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001473459,0.0002048775,0.0001599723,0.0001631331,0.0001127316,0.0001717624,0.0001413605,0.0002784658,0.0005416491],"category_scores_gemma":[0.0001313469,0.0001665862,0.0001784453,0.00006511343,0.0002051107,0.0002847266,0.0001426993,0.0002412797,0.0002460301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005437235,"about_ca_system_score_gemma":0.0002534653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007395888,"about_ca_topic_score_gemma":0.001470951,"domain_scores_codex":[0.9999325,0.000006451564,0.000005063707,0.00001739144,0.00002363087,0.00001504481],"domain_scores_gemma":[0.9999348,0.00001598317,0.00001649751,0.000006592743,0.0000111146,0.0000150623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008753314,0.000003474497,0.0000178651,0.00001307866,0.000001170535,0.00001052907,0.000004327997,0.00008436058,0.9993736,0.0000665803,0.00001781023,0.0003984583],"study_design_scores_gemma":[0.000006892137,0.00003912665,0.0002805764,0.00000122094,0.000004480747,0.00004457903,0.000006077582,0.001693704,0.996581,0.00003214228,0.0013047,0.000005438731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738075,0.00176393,0.02135706,0.0002138641,0.00005784514,0.00006508861,0.0002092701,0.0004723829,0.00205319],"genre_scores_gemma":[0.9883059,0.0004791974,0.009006426,0.00006273336,0.00001431879,0.00003005482,0.0001218655,0.00003343776,0.0019459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007395888,"threshold_uncertainty_score":0.003945053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00450077025742796,"score_gpt":0.1985238619635449,"score_spread":0.194023091706117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}