{"id":"W2001111653","doi":"10.1523/jneurosci.2922-06.2006","title":"Age-Related Changes in Iron Homeostasis and Cell Death in the Cerebellum of Ceruloplasmin-Deficient Mice","year":2006,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"Ceruloplasmin; DMT1; Ferritin; Homeostasis; Ferroportin; Neurodegeneration; Cerebellum; Cell biology; Biology; Transporter; Chemistry; Ferrous; Biochemistry; Metabolism; Endocrinology; Internal medicine; Iron homeostasis; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002205035,0.0009169464,0.0006459788,0.001647328,0.0003155644,0.0005793085,0.0004739849,0.0009135794,0.001633667],"category_scores_gemma":[0.0002924747,0.000491537,0.0005512811,0.0003452065,0.0005701594,0.0005081812,0.0003487534,0.0009695427,0.000753602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005632403,"about_ca_system_score_gemma":0.000283432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001669412,"about_ca_topic_score_gemma":0.00195594,"domain_scores_codex":[0.9996814,0.00002034864,0.00005625744,0.0001244638,0.00007827342,0.00003928151],"domain_scores_gemma":[0.99925,0.00004270119,0.000397253,0.0000456585,0.00006702487,0.0001972522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000229151,0.00006176326,0.000838716,0.00003534273,0.00002451074,0.0004985189,0.00008007538,0.00008779653,0.9965659,0.0001154236,0.00006558164,0.001397306],"study_design_scores_gemma":[0.0001898332,0.001667085,0.1367484,0.00007380636,0.0002602211,0.00994051,0.0003198129,0.002660471,0.842009,0.000754814,0.005306046,0.00007009885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903951,0.001871359,0.004234619,0.0001562653,0.00005420379,0.00004304761,0.001792458,0.0003712563,0.001081725],"genre_scores_gemma":[0.9843859,0.001841007,0.004262904,0.0001245534,0.00002781408,0.00009359551,0.001863147,0.0002768926,0.007124208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001669412,"threshold_uncertainty_score":0.005465209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584145043621803,"score_gpt":0.246602269623287,"score_spread":0.2307608191870689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}