{"id":"W2001327595","doi":"10.1371/journal.pone.0012935","title":"Protective Action of Resveratrol in Human Skin: Possible Involvement of Specific Receptor Binding Sites","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Resveratrol; Piceatannol; Chemistry; HaCaT; Pharmacology; Sodium nitroprusside; Polyphenol; Mechanism of action; Biochemistry; Human skin; Apoptosis; Nitric oxide; Biology; Antioxidant; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002597663,0.0003750524,0.0003269313,0.0002442766,0.0001701636,0.0002502908,0.0003917467,0.0006603033,0.003580969],"category_scores_gemma":[0.0002281468,0.0002048465,0.0007378834,0.0001208692,0.0002407294,0.0002660856,0.0001848671,0.0003469854,0.0008483123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796197,"about_ca_system_score_gemma":0.0001344878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007113938,"about_ca_topic_score_gemma":0.0009238894,"domain_scores_codex":[0.9997476,0.00008302943,0.00001132879,0.00006303752,0.00003997916,0.00005513227],"domain_scores_gemma":[0.9998366,0.00004421228,0.00004784912,0.00002018403,0.00003196178,0.00001921937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004119975,0.00004730731,0.0007474315,0.0002615431,0.00004180194,0.0001931264,0.00004440882,0.00009096296,0.9949786,0.0001441891,0.00007927675,0.002959346],"study_design_scores_gemma":[0.0000597323,0.001887221,0.03984984,0.00005613771,0.0002433646,0.002824385,0.0002144372,0.001319823,0.9492671,0.0002978202,0.003950505,0.00002952511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714399,0.01574761,0.00923638,0.0002105673,0.00006539788,0.00007008531,0.0003521482,0.0001148618,0.002762989],"genre_scores_gemma":[0.9934197,0.002699009,0.002266309,0.00009440374,0.00001544029,0.00002388271,0.0002382717,0.000009240153,0.001233719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003580969,"threshold_uncertainty_score":0.01197952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07598997823534064,"score_gpt":0.2927182406646154,"score_spread":0.2167282624292747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}