{"id":"W2001334954","doi":"10.1161/circulationaha.113.006381","title":"Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating T Helper-1 Adaptive Immunity","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Immunology; Acquired immune system; Chemokine; Immune system; Macrophage; CD40; Population; Innate immune system; B cell; Cell biology; Antigen-presenting cell; Medicine; Biology; T cell; Antibody; Cytotoxic T cell; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003346051,0.0005861382,0.0002814769,0.000285433,0.0001217029,0.0002452724,0.000155915,0.0003376263,0.002616153],"category_scores_gemma":[0.0002103623,0.0001260769,0.0001935975,0.00009192383,0.0002871975,0.0001366678,0.0002458294,0.0009058758,0.0005505468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001244747,"about_ca_system_score_gemma":0.0001709557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001161426,"about_ca_topic_score_gemma":0.0001314754,"domain_scores_codex":[0.9998387,0.00005326048,0.00001239356,0.00002315171,0.00002649182,0.00004596343],"domain_scores_gemma":[0.9998122,0.00002604611,0.00005967463,0.00002168386,0.00002157018,0.00005882324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001041461,0.0001682445,0.001649971,0.0001259231,0.00001565178,0.000276808,0.00003223033,0.00005991465,0.9911683,0.0002416973,0.0002707555,0.004949042],"study_design_scores_gemma":[0.0006786798,0.005221906,0.03699773,0.00007920466,0.0002650122,0.004419654,0.0001498822,0.001517143,0.9355485,0.001152944,0.01395248,0.00001687404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931335,0.002265076,0.001985358,0.0003043509,0.00006842037,0.00003478388,0.00009737098,0.0001790551,0.001932137],"genre_scores_gemma":[0.9944043,0.001147181,0.002194205,0.0001925289,0.0001287602,0.00004160382,0.0001489927,0.00002734666,0.001715027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002616153,"threshold_uncertainty_score":0.008751929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645915252583505,"score_gpt":0.219818139260537,"score_spread":0.2033589867347019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}