{"id":"W2001356048","doi":"10.1016/j.ahj.2008.01.002","title":"A randomized, double-blind, placebo-controlled, multicenter study to evaluate the cardioprotective effects of MC-1 in patients undergoing high-risk coronary artery bypass graft surgery: MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery Trial (MEND-CABG) II—study design and rationale","year":2008,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute; Medicure (Canada)","funders":"","keywords":"Medicine; Placebo; Artery; Surgery; Coronary artery bypass surgery; Randomized controlled trial; Multicenter study; Cardiology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00254662,0.003047302,0.005347132,0.0005723878,0.0006821612,0.001042892,0.001262358,0.002457195,0.005762347],"category_scores_gemma":[0.002616302,0.001072246,0.00131481,0.0005649385,0.001957761,0.001005672,0.0004756688,0.00290357,0.00121145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004539373,"about_ca_system_score_gemma":0.001275862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005507182,"about_ca_topic_score_gemma":0.001254312,"domain_scores_codex":[0.999051,0.0004971643,0.00007306132,0.0001723818,0.00007484843,0.0001315619],"domain_scores_gemma":[0.9990669,0.0002453937,0.0002043152,0.0001057508,0.00009104937,0.0002866517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9838547,0.00569347,0.0003842132,0.0006945952,0.0005467138,0.00002340964,0.00002896621,0.0001472742,0.002570006,0.0001687018,0.0004349952,0.005452884],"study_design_scores_gemma":[0.9714673,0.0269268,0.0005074236,0.00001825701,0.0003283796,0.00001271607,0.000007293128,0.0001011737,0.0002272126,0.000093865,0.000300311,0.000009179888],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9460357,0.009346546,0.002898858,0.001700925,0.001492435,0.0321461,0.002510957,0.0003634542,0.00350503],"genre_scores_gemma":[0.9214061,0.007654807,0.009301119,0.003571155,0.002611113,0.04725289,0.002259759,0.0000656755,0.005877359],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.005762347,"threshold_uncertainty_score":0.01927692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05698217506158507,"score_gpt":0.3159768515918872,"score_spread":0.2589946765303021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}