{"id":"W2001465189","doi":"10.1002/iub.557","title":"Signaling epigenetics: Novel insights on cell signaling and epigenetic regulation","year":2011,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México; Consejo Nacional de Ciencia y Tecnología","keywords":"Epigenetics; Crosstalk; Chromatin; Signal transduction; Biology; Transcription factor; Cell fate determination; Cell biology; Transcriptional regulation; Regulation of gene expression; Chromatin remodeling; Histone; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000339753,0.0006614304,0.0009297427,0.000230133,0.0001800619,0.00007876183,0.0003139345,0.0008560303,0.00003957687],"category_scores_gemma":[0.0001383963,0.0006076494,0.0003381221,0.0001836517,0.00009778575,0.000004710084,0.0001693501,0.0002954777,0.00005144985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003402228,"about_ca_system_score_gemma":0.0002818691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001211267,"about_ca_topic_score_gemma":0.000005750268,"domain_scores_codex":[0.9972366,0.0002186959,0.0008732604,0.001001782,0.0002528601,0.0004168123],"domain_scores_gemma":[0.9981461,0.0001001064,0.0005992249,0.0007137312,0.0001363605,0.0003045002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008624166,0.0005006975,0.00005339535,0.008995157,0.0005528081,0.00000840784,0.0003851771,0.0009369138,0.1304711,0.000628101,0.0002202968,0.8571618],"study_design_scores_gemma":[0.0003777854,0.000440046,0.00002854921,0.001420906,0.0004378318,0.000003023816,0.0000132058,0.00002928006,0.04800778,0.0002530387,0.9481565,0.0008320578],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004630457,0.9874994,0.005216634,0.000004714121,0.0003474947,0.0007135525,0.00004170193,0.00002476641,0.001521301],"genre_scores_gemma":[0.01493131,0.9807553,0.002038048,0.00007682609,0.0009417965,0.00007626147,0.0004944544,0.0001567651,0.0005292905],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9479362,"threshold_uncertainty_score":0.9996375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05447690119742317,"score_gpt":0.2916750343996019,"score_spread":0.2371981332021788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}