{"id":"W2001465189","doi":"10.1002/iub.557","title":"Signaling epigenetics: Novel insights on cell signaling and epigenetic regulation","year":2011,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México; Consejo Nacional de Ciencia y Tecnología","keywords":"Epigenetics; Crosstalk; Chromatin; Signal transduction; Biology; Transcription factor; Cell fate determination; Cell biology; Transcriptional regulation; Regulation of gene expression; Chromatin remodeling; Histone; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008351233,0.001285044,0.001238663,0.00205872,0.0004207186,0.00123024,0.001345754,0.002029511,0.002431475],"category_scores_gemma":[0.000587999,0.0003545923,0.0003816919,0.001984267,0.002263339,0.002946775,0.0009718334,0.002936875,0.002386873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001308713,"about_ca_system_score_gemma":0.0008046301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006671384,"about_ca_topic_score_gemma":0.001192245,"domain_scores_codex":[0.9997875,0.00004427627,0.00002063508,0.0000416184,0.00008647851,0.00001946419],"domain_scores_gemma":[0.9997173,0.0001388732,0.00002538719,0.00001929711,0.00006448838,0.00003465271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005908747,0.00006727414,0.0001795613,0.005921093,0.00007195868,0.0005258542,0.0001845527,0.0009227231,0.01071873,0.04070832,0.03864627,0.9019945],"study_design_scores_gemma":[0.00000976713,0.00003958106,0.0003381993,0.0007539985,0.00002422733,0.001390912,0.00005534025,0.0001769096,0.001700921,0.01144883,0.9840418,0.00001940555],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001254075,0.9954146,0.00106272,0.0007771052,0.0006440675,0.000003495318,0.000008478299,0.00001493178,0.001949199],"genre_scores_gemma":[0.001359679,0.9949151,0.0007974321,0.0004721879,0.0007103887,0.000007617144,0.00002022071,0.000003510845,0.00171389],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002431475,"threshold_uncertainty_score":0.009495378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05447690119742317,"score_gpt":0.2916750343996019,"score_spread":0.2371981332021788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}