{"id":"W2001481979","doi":"10.1186/1471-213x-9-9","title":"In vitroculture and somatic cell nuclear transfer affect imprinting of SNRPN gene in pre- and post-implantation stages of development in cattle","year":2009,"lang":"en","type":"article","venue":"BMC Developmental Biology","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"Institute of Human Development, Child and Youth Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Genomic imprinting; Biology; Somatic cell nuclear transfer; Imprinting (psychology); Reprogramming; DNA methylation; Epigenetics; Methylation; Genetics; Somatic cell; Embryo; Andrology; Molecular biology; Gene expression; Gene; Blastocyst; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001858411,0.000116113,0.0002018458,0.0001050225,0.00001470906,0.000004183379,0.00006775554,0.0001262465,0.000006034248],"category_scores_gemma":[0.00002236196,0.0001091268,0.00001537891,0.00008075091,0.00003698473,0.000007172021,0.00006053645,0.00005396337,4.901257e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001654572,"about_ca_system_score_gemma":0.00006304119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006493025,"about_ca_topic_score_gemma":0.0002822046,"domain_scores_codex":[0.9991499,0.00005081506,0.0003511108,0.0002294529,0.00003980266,0.0001788888],"domain_scores_gemma":[0.9998387,0.00001293599,0.00005419012,0.00005295034,0.00001609174,0.00002511426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002221136,0.00004165759,0.2577223,0.00007340223,0.000003527723,5.072297e-7,0.001205447,0.000004264036,0.7383645,0.000009391469,4.256539e-7,0.002552361],"study_design_scores_gemma":[0.0005774674,0.0001090649,0.5855564,0.0000253076,0.000001445309,0.00002125517,0.0002775511,0.00000538291,0.4133169,0.00001227143,0.00002022706,0.00007667077],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993395,0.0002618643,0.00009766156,0.00001270477,0.0000195765,0.000205451,0.000005133156,0.000001772894,0.00005628778],"genre_scores_gemma":[0.987294,0.000111219,0.0124853,0.00004171815,0.000004256918,0.000005913331,0.00003876054,0.000006384412,0.00001240503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3278341,"threshold_uncertainty_score":0.4450061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005892786256505913,"score_gpt":0.2255709578897011,"score_spread":0.2196781716331952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}