{"id":"W2001481979","doi":"10.1186/1471-213x-9-9","title":"In vitroculture and somatic cell nuclear transfer affect imprinting of SNRPN gene in pre- and post-implantation stages of development in cattle","year":2009,"lang":"en","type":"article","venue":"BMC Developmental Biology","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"Institute of Human Development, Child and Youth Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Genomic imprinting; Biology; Somatic cell nuclear transfer; Imprinting (psychology); Reprogramming; DNA methylation; Epigenetics; Methylation; Genetics; Somatic cell; Embryo; Andrology; Molecular biology; Gene expression; Gene; Blastocyst; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002093964,0.0002261886,0.0002063054,0.0002321012,0.000182479,0.0002625433,0.000203459,0.0002510616,0.001145334],"category_scores_gemma":[0.0002929726,0.0001097827,0.0001866248,0.0001549979,0.0002474847,0.0001386973,0.0001838922,0.0003013015,0.0001883537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003928319,"about_ca_system_score_gemma":0.0001728026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002071134,"about_ca_topic_score_gemma":0.002547306,"domain_scores_codex":[0.9997787,0.00004464324,0.00001758551,0.00005156146,0.00004898543,0.00005845209],"domain_scores_gemma":[0.9997643,0.00008170176,0.00007908438,0.00001443704,0.00001446997,0.00004603607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002956235,0.0000425717,0.003959931,0.00003594041,0.00001255739,0.0001005027,0.00008779008,0.00005446884,0.9935881,0.0000379774,0.00001979511,0.001764761],"study_design_scores_gemma":[0.00001956133,0.001670764,0.1458538,0.00001915994,0.0000841614,0.00058489,0.0002891194,0.0005723084,0.8480727,0.0000673762,0.002754735,0.00001145196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977215,0.0009676797,0.000609455,0.00001991925,0.00001165351,0.00000749375,0.0001364495,0.000006738715,0.0005191626],"genre_scores_gemma":[0.9959838,0.0009885194,0.000610646,0.00003518286,0.00001011841,0.00002716562,0.0004749026,0.000009781377,0.001859868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071134,"threshold_uncertainty_score":0.004118145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005892786256505913,"score_gpt":0.2255709578897011,"score_spread":0.2196781716331952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}