{"id":"W2001555312","doi":"10.1211/0022357044625","title":"Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3,3′-di-<i>O</i>-gallate from <i>Myrica rubra</i> via Fas-mediated pathway","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacy and Pharmacology","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Apoptosis; Fas ligand; MCF-7; Gallate; Myrica rubra; Cancer cell; Biology; Chemistry; Cancer research; Programmed cell death; Molecular biology; Cancer; Biochemistry; Pharmacology; Human breast; Botany; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006083328,0.0002261817,0.0001551746,0.00014119,0.00009149025,0.00008248607,0.0001007744,0.0001217748,0.0006999793],"category_scores_gemma":[0.0000435822,0.00008211744,0.0001788763,0.0001300606,0.00006576604,0.00007405795,0.00008193503,0.0002850683,0.0001963421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001244632,"about_ca_system_score_gemma":0.0001390805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008649713,"about_ca_topic_score_gemma":0.001020331,"domain_scores_codex":[0.9999543,0.000007343232,0.000004081445,0.000006972657,0.00001437357,0.00001290428],"domain_scores_gemma":[0.9999814,0.000004126597,0.000004594385,0.000002345915,0.000003900922,0.000003591978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006404291,0.00002008117,0.00009146626,0.00003926269,0.000002396081,0.0000505867,0.00001178059,0.00002262516,0.9984764,0.00002868118,0.00002016038,0.001172454],"study_design_scores_gemma":[0.00001567642,0.0005477616,0.003717333,0.00000465798,0.00001446413,0.0002677579,0.00001993398,0.0002383481,0.9935714,0.0000220237,0.001578325,0.000002398125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916391,0.004157481,0.001366272,0.0001177652,0.0000261097,0.00003114747,0.0002896522,0.00005214503,0.002320343],"genre_scores_gemma":[0.9912116,0.003434855,0.001915735,0.00006518389,0.000007258108,0.00003356906,0.0006943178,0.000007257036,0.002630253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008649713,"threshold_uncertainty_score":0.002341628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048653658219946,"score_gpt":0.2554028383448484,"score_spread":0.244916301762649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}