{"id":"W2001557690","doi":"10.1074/jbc.m114.585604","title":"Regulation of the Sarcoplasmic Reticulum Calcium Pump by Divergent Phospholamban Isoforms in Zebrafish","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"","keywords":"Phospholamban; Endoplasmic reticulum; Zebrafish; Calcium; Gene isoform; Sarcoplasm; Ryanodine receptor 2; Cell biology; Calcium pump; Chemistry; Internal medicine; Biology; Ryanodine receptor; Biochemistry; Medicine; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001086829,0.0002698494,0.0002116241,0.0002639848,0.0002040406,0.0001958179,0.0002890027,0.0003538594,0.0006276907],"category_scores_gemma":[0.0001249141,0.0002297765,0.0004033004,0.00008279333,0.0003224583,0.0002302139,0.000291693,0.0005499675,0.000228746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009302602,"about_ca_system_score_gemma":0.0004177239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004485888,"about_ca_topic_score_gemma":0.006487394,"domain_scores_codex":[0.9998817,0.000008184821,0.00001299191,0.00003930145,0.00003675497,0.00002106112],"domain_scores_gemma":[0.9999007,0.000008975654,0.00003882087,0.000007972201,0.00001396533,0.00002959124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003845108,0.000003074618,0.0002079465,0.0000126213,0.000002038258,0.00005445579,0.000016675,0.00006964131,0.9990731,0.000111174,0.00001177515,0.0003989831],"study_design_scores_gemma":[0.00006565582,0.0002411525,0.02461602,0.00001904521,0.00004740942,0.0005616395,0.000109241,0.002722273,0.9684814,0.0001847886,0.002917635,0.00003366554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951112,0.0004346551,0.002816247,0.00009752943,0.00001789039,0.00001925319,0.0002419943,0.0000679807,0.001193258],"genre_scores_gemma":[0.9914106,0.0004274876,0.004532355,0.00009570247,0.000004066495,0.00004802897,0.0002366909,0.00003649442,0.003208718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004485888,"threshold_uncertainty_score":0.008919537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0238065651305971,"score_gpt":0.2776518536826965,"score_spread":0.2538452885520994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}