{"id":"W2001566941","doi":"10.1021/bc060260r","title":"Construction and Evaluation of the Tumor Imaging Properties of<sup>123</sup>I-Labeled Recombinant and Enzymatically Generated Fab Fragments of the TAG-72 Monoclonal Antibody CC49","year":2007,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Monoclonal antibody; Pichia pastoris; Molecular biology; Chemistry; Recombinant DNA; Glycoprotein; Antibody; Melanoma; Gene; Cancer research; Biochemistry; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001798797,0.0002778542,0.00017432,0.0001166381,0.0000778922,0.0001632206,0.0001812647,0.0002411332,0.0004029657],"category_scores_gemma":[0.0001309802,0.00008268539,0.0001622897,0.0001776359,0.0001229144,0.0001355459,0.00008906861,0.0003510441,0.0002329514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003235333,"about_ca_system_score_gemma":0.0000954081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001078276,"about_ca_topic_score_gemma":0.0005804437,"domain_scores_codex":[0.9999225,0.0000141744,0.000005394601,0.00001543007,0.0000245092,0.0000179719],"domain_scores_gemma":[0.9999201,0.00001698903,0.00002135195,0.000009806897,0.00001898004,0.00001278142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002798422,0.000005848929,0.00006416484,0.000009724004,0.000001284385,0.00001259361,0.000004661083,0.00005896093,0.999441,0.00001964906,0.000009891209,0.0003441672],"study_design_scores_gemma":[0.000003413873,0.00009925524,0.00108998,0.000001418803,0.000005987398,0.00007937201,0.000007012907,0.0006577467,0.9972977,0.000008055204,0.0007482157,0.000001839261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924859,0.0006383161,0.00547758,0.00005571823,0.00001027319,0.00002878053,0.0003851574,0.00004819331,0.0008699538],"genre_scores_gemma":[0.9864624,0.0006874582,0.01015495,0.00004524259,0.000006158413,0.00004441637,0.001241474,0.00003566697,0.001322227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001078276,"threshold_uncertainty_score":0.00234741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555123157900684,"score_gpt":0.2935565014625527,"score_spread":0.2680052698835458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}