{"id":"W2001566941","doi":"10.1021/bc060260r","title":"Construction and Evaluation of the Tumor Imaging Properties of<sup>123</sup>I-Labeled Recombinant and Enzymatically Generated Fab Fragments of the TAG-72 Monoclonal Antibody CC49","year":2007,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Monoclonal antibody; Pichia pastoris; Molecular biology; Chemistry; Recombinant DNA; Glycoprotein; Antibody; Melanoma; Gene; Cancer research; Biochemistry; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009544285,0.000162682,0.0003143646,0.00003405316,0.0001157723,0.00001247932,0.0001313527,0.00007048703,0.00005595107],"category_scores_gemma":[0.0002423553,0.00009063137,0.00008019505,0.0001808953,0.0008521719,0.00004734338,0.0001660837,0.0001883897,6.036352e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000388155,"about_ca_system_score_gemma":0.0002336209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001041154,"about_ca_topic_score_gemma":0.000001417688,"domain_scores_codex":[0.998261,0.00008008636,0.0005256324,0.0002282859,0.0006686203,0.0002363269],"domain_scores_gemma":[0.9988263,0.00005369324,0.0002599983,0.0002546408,0.0005215675,0.00008384875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002947953,0.0001022844,0.07143757,0.0008004435,0.00009009155,0.000001878622,0.0001830889,0.000004541975,0.923968,0.00003877248,0.00003273275,0.003045871],"study_design_scores_gemma":[0.001547131,0.0000419668,0.03458739,0.0005759875,0.0001402249,0.0001437951,0.0004287878,0.006287154,0.9559534,0.0001129265,0.00008657922,0.00009464456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967664,0.001636142,0.000007486018,0.0004765872,0.00005798708,0.0005412968,0.00002397017,0.000006879609,0.0004832472],"genre_scores_gemma":[0.9991676,0.0001222801,0.0003278219,0.00004670921,0.00005126319,0.000009489158,0.00001493669,0.00001218393,0.0002477543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03685018,"threshold_uncertainty_score":0.369584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555123157900684,"score_gpt":0.2935565014625527,"score_spread":0.2680052698835458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}