{"id":"W2001589419","doi":"10.1006/dbio.2001.0215","title":"Factors Controlling the Loss of Immunoreactive Somatic Histone H1 from Blastomere Nuclei in Oocyte Cytoplasm: A Potential Marker of Nuclear Reprogramming","year":2001,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Cegep de Saint Hyacinthe","funders":"Medical Research Council","keywords":"Biology; Telophase; Interphase; Metaphase; Somatic cell; Blastomere; Cell biology; Cell nucleus; Cytoplast; Oocyte; Cell cycle; Molecular biology; Mitosis; Maturation promoting factor; Histone; Cytoplasm; Embryo; Genetics; Cell; Chromosome; Embryogenesis; DNA; Gene; Cyclin-dependent kinase 1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002035851,0.0004117195,0.0002436165,0.0004501804,0.0002624925,0.0006251595,0.0003343172,0.0003038366,0.002775519],"category_scores_gemma":[0.0003204522,0.0003583514,0.0002370842,0.0001626609,0.0005366929,0.0003869794,0.0003759491,0.0008143786,0.0008850173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006118742,"about_ca_system_score_gemma":0.000439338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001223941,"about_ca_topic_score_gemma":0.002522608,"domain_scores_codex":[0.9997544,0.00002182147,0.00002181203,0.00008623772,0.0000503525,0.00006542232],"domain_scores_gemma":[0.9995246,0.0001255545,0.0001257212,0.0000708227,0.00003837681,0.000114966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004157891,0.000005880352,0.0001629401,0.000009382404,0.000001486227,0.00003511167,0.0000115875,0.00001132863,0.9990467,0.0001990807,0.00001919595,0.0004557529],"study_design_scores_gemma":[0.00001049352,0.00005090658,0.008050187,0.000003246596,0.0000112364,0.000185283,0.00003942762,0.0002246401,0.9896208,0.0001013771,0.00169732,0.000005060649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978651,0.001929895,0.01121371,0.0002590103,0.00007783926,0.00006102727,0.00125183,0.0003481159,0.006207619],"genre_scores_gemma":[0.9881242,0.0004633777,0.002531998,0.0001022288,0.00002255298,0.0000410751,0.001145276,0.0001831476,0.0073862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002775519,"threshold_uncertainty_score":0.009285033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858988712069955,"score_gpt":0.2684332316192014,"score_spread":0.2498433444985018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}