{"id":"W2001611645","doi":"10.1016/s0304-3940(02)00469-x","title":"Calpain-dependent neurofilament breakdown in anoxic and ischemic rat central axons","year":2002,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Calpain; EGTA; Neurofilament; Proteolysis; Biology; Axoplasm; Dephosphorylation; Biochemistry; Chemistry; Axon; Cell biology; Internal medicine; Anatomy; Biophysics; Phosphorylation; Calcium; Enzyme; Medicine; Immunology; Phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008804217,0.0001121409,0.00007132491,0.00005892307,0.00007979995,0.00004253835,0.0001033413,0.00005167552,0.00002528518],"category_scores_gemma":[0.00005074062,0.0001058165,0.0000334351,0.0001239031,0.000149295,0.00001038786,0.00006462977,0.00009874889,0.000004553821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001781925,"about_ca_system_score_gemma":0.000008254782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000934483,"about_ca_topic_score_gemma":0.000008799325,"domain_scores_codex":[0.9989524,0.00005971105,0.0001339217,0.0004130624,0.0001556305,0.000285261],"domain_scores_gemma":[0.9996664,0.000006367696,0.00003812223,0.0001839405,0.000008020254,0.00009715502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001061532,0.00003229449,0.007546917,0.00000431788,5.662914e-7,0.00001223988,0.00003345342,0.0002572954,0.9845886,0.000005138338,0.006619854,0.0008886593],"study_design_scores_gemma":[0.00189841,0.0003500028,0.1093002,0.00002522171,0.00001317221,0.000293134,0.00006186761,0.01019108,0.7511749,0.00000764196,0.1260517,0.0006326785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993167,0.00007084441,0.0009166251,0.005035114,0.0004294357,0.0001864187,0.00000236914,0.00001434324,0.0001777846],"genre_scores_gemma":[0.9877079,0.00008094653,0.00003893725,0.01149698,0.00008174853,0.00001383139,0.000004828296,0.000009066236,0.0005658236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2334137,"threshold_uncertainty_score":0.4315072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01003824761898843,"score_gpt":0.2021860857511505,"score_spread":0.1921478381321621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}