{"id":"W2001686878","doi":"10.1016/j.jim.2012.08.017","title":"A simple technique to enhance the humoral immune response to intracellular protein antigens in genetic immunizations","year":2012,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Antigen; Immune system; Biology; Intracellular; Fusion protein; Humoral immunity; Secretion; Intracellular parasite; Molecular biology; Virology; Immunology; Cell biology; Recombinant DNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003695354,0.0006711684,0.0004533177,0.0006138965,0.0003511273,0.000356597,0.0004922861,0.0007837203,0.00180131],"category_scores_gemma":[0.0002913478,0.0003202686,0.0006862807,0.0002734356,0.0004331298,0.0004744593,0.0004918142,0.001530491,0.0008711179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001924289,"about_ca_system_score_gemma":0.0002705284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001922416,"about_ca_topic_score_gemma":0.000421386,"domain_scores_codex":[0.999673,0.0000658659,0.00002330812,0.00005460939,0.0001331735,0.00004993416],"domain_scores_gemma":[0.9997874,0.00005858285,0.0000417327,0.00005257777,0.00002423665,0.00003555867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003066145,0.00003284675,0.00003207713,0.00004446912,0.000004597268,0.00003809236,0.00001004455,0.00002925426,0.9968296,0.0002086894,0.00008936194,0.002650377],"study_design_scores_gemma":[0.00004406014,0.0003901536,0.0006703014,0.000007614447,0.00004038054,0.0005606018,0.000008568013,0.0003462791,0.9906939,0.0002600368,0.00696537,0.00001271635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5773678,0.006975452,0.4006422,0.001152107,0.00105854,0.001093436,0.0006554233,0.002033796,0.009021183],"genre_scores_gemma":[0.749948,0.003983534,0.2292587,0.0006352449,0.0002298316,0.0007725817,0.0008771396,0.0003142958,0.01398071],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.00180131,"threshold_uncertainty_score":0.00602597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01935667875093515,"score_gpt":0.3677847626198599,"score_spread":0.3484280838689247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}