{"id":"W2001701683","doi":"10.1038/nmeth.1941","title":"Phosphorylation sites of higher stoichiometry are more conserved","year":2012,"lang":"en","type":"letter","venue":"Nature Methods","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Phosphorylation; Stoichiometry; Computational biology; Chemistry; Biology; Evolutionary biology; Cell biology; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000614527,0.0006856204,0.0007694792,0.0004092907,0.0006426711,0.001191809,0.0007148369,0.001524492,0.01104667],"category_scores_gemma":[0.00120457,0.0003316721,0.0004656427,0.0003812899,0.0006542204,0.001030152,0.0003894574,0.00201292,0.002793554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005059533,"about_ca_system_score_gemma":0.0001679149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002381236,"about_ca_topic_score_gemma":0.0004801922,"domain_scores_codex":[0.9996164,0.00005327515,0.0000419614,0.0001541353,0.00006246794,0.00007183532],"domain_scores_gemma":[0.9991311,0.0001883452,0.0001465064,0.0002204606,0.00008990365,0.0002237046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001353134,0.00017738,0.002850266,0.000263995,0.0000649881,0.002833743,0.00009910514,0.0008452432,0.9538006,0.01502399,0.002961316,0.01972613],"study_design_scores_gemma":[0.0007821213,0.0009150022,0.02756798,0.00006517643,0.0002203555,0.01509744,0.0001874692,0.01177016,0.8577673,0.02475326,0.06072368,0.0001500083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8868026,0.005950755,0.04795145,0.01350178,0.005452854,0.0001259356,0.0006399214,0.001575909,0.03799882],"genre_scores_gemma":[0.9751717,0.0008909111,0.01236129,0.00514612,0.0008181373,0.00005010379,0.0004293235,0.000274351,0.00485801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01104667,"threshold_uncertainty_score":0.03695482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0248729926154066,"score_gpt":0.346663863524405,"score_spread":0.3217908709089984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}