{"id":"W2001736616","doi":"10.1016/j.pep.2007.03.004","title":"Over-expression and refolding of MAP kinase phosphatase 3","year":2007,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"DUSP6; Phosphatase; Kinase; MAPK/ERK pathway; Biochemistry; Protein kinase A; Phosphorylation; Molecular biology; Chemistry; Biology; Cell biology; Protein phosphatase 2","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004415241,0.0001493498,0.00012686,0.00005667424,0.0001120084,0.00002212928,0.0001110541,0.0001486291,0.00002203683],"category_scores_gemma":[0.0001462464,0.0001310427,0.00002829611,0.00006390228,0.00009630963,0.00001873655,0.0001390748,0.0000773459,0.000001688086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007254645,"about_ca_system_score_gemma":0.00001812545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002441502,"about_ca_topic_score_gemma":0.000001908154,"domain_scores_codex":[0.9989535,0.00005031032,0.0002794848,0.000377362,0.0001566118,0.000182797],"domain_scores_gemma":[0.9992235,0.00001583968,0.0002076721,0.0003689569,0.00006217795,0.000121888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002810832,0.00005411169,0.0006583619,0.000104436,0.000003926473,0.000001470304,0.00003389472,7.184861e-7,0.9829124,0.001183485,0.000586756,0.01417931],"study_design_scores_gemma":[0.0005945695,0.0001153875,0.002416896,0.0001974002,0.000006379855,0.000002811777,0.00003969121,0.00001614983,0.9802036,0.0003238732,0.01592984,0.0001534042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9429474,0.04825974,0.007620373,0.0001130259,0.00006529535,0.0007731596,0.00007548177,0.00002508905,0.000120477],"genre_scores_gemma":[0.990855,0.0003954217,0.0081749,0.00004725658,0.00008114405,0.00005857946,0.0002359697,0.00001800263,0.0001336728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04790769,"threshold_uncertainty_score":0.5343768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00965609625073137,"score_gpt":0.2585967616035946,"score_spread":0.2489406653528632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}