{"id":"W2001736616","doi":"10.1016/j.pep.2007.03.004","title":"Over-expression and refolding of MAP kinase phosphatase 3","year":2007,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"DUSP6; Phosphatase; Kinase; MAPK/ERK pathway; Biochemistry; Protein kinase A; Phosphorylation; Molecular biology; Chemistry; Biology; Cell biology; Protein phosphatase 2","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000346783,0.0006007665,0.0005056079,0.0002590034,0.0004329473,0.0005813052,0.0004855759,0.0003852504,0.0005489207],"category_scores_gemma":[0.0002917345,0.0003097024,0.0006463071,0.0005582708,0.0004231655,0.0003631121,0.0005084516,0.001337179,0.000545555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009485043,"about_ca_system_score_gemma":0.0007070104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003255351,"about_ca_topic_score_gemma":0.002969879,"domain_scores_codex":[0.9997379,0.00002821192,0.00002973731,0.0000521699,0.00007311727,0.00007869198],"domain_scores_gemma":[0.9998257,0.00004231202,0.00003421614,0.00003794023,0.00003072531,0.00002912059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001267775,0.00004218631,0.0001946652,0.00004526832,0.00001473178,0.0001176567,0.00005129133,0.0003452995,0.9970556,0.0004434479,0.0001474041,0.001415595],"study_design_scores_gemma":[0.0000116978,0.00002636291,0.0006532095,0.000002770782,0.00001233117,0.0001069288,0.00002175323,0.001182065,0.9946015,0.00009921278,0.003275618,0.000006519318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669952,0.001677129,0.0259379,0.0005055465,0.0001958315,0.0001377474,0.002366791,0.0003764701,0.001807371],"genre_scores_gemma":[0.9594935,0.001901748,0.02262687,0.0001885162,0.0000272202,0.0001065854,0.005933311,0.0002385059,0.009483692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003255351,"threshold_uncertainty_score":0.006881893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00965609625073137,"score_gpt":0.2585967616035946,"score_spread":0.2489406653528632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}