{"id":"W2001744429","doi":"10.1177/095632020401500402","title":"Mutations and Polymorphisms Associated with Antiretroviral Drugs in HIV-1C-Infected African Patients","year":2004,"lang":"en","type":"article","venue":"Antiviral chemistry & chemotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fogarty International Center; National Institutes of Health","keywords":"Stavudine; Didanosine; Resistance mutation; Nevirapine; Efavirenz; Zidovudine; Lamivudine; Virology; Reverse transcriptase; Reverse-transcriptase inhibitor; Biology; Viral load; Regimen; Medicine; Internal medicine; Virus; Viral disease; Antiretroviral therapy; Polymerase chain reaction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001818578,0.0002282088,0.0002263798,0.001041158,0.0007230376,0.0004361466,0.0001376718,0.000472673,0.001669485],"category_scores_gemma":[0.001296903,0.0001903275,0.0001560914,0.001118164,0.00025681,0.0002476906,0.0001714069,0.0003499253,0.0001501866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003527844,"about_ca_system_score_gemma":0.0002572038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003866418,"about_ca_topic_score_gemma":0.004564424,"domain_scores_codex":[0.9997728,0.00005637279,0.00002706985,0.00004641134,0.00003801167,0.00005936107],"domain_scores_gemma":[0.99963,0.0000939834,0.0001252227,0.00001699075,0.00004267483,0.00009107263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004543886,0.0001061179,0.9852529,0.00002469706,0.00003058697,0.001386264,0.0003457588,0.00007393008,0.006101818,0.00007409849,0.0001320792,0.006017229],"study_design_scores_gemma":[0.00004028354,0.0003019065,0.9935819,0.0000240147,0.00002518294,0.004125338,0.0004233761,0.0002562695,0.0006229156,0.00006299325,0.0005269182,0.000008904663],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993584,0.0002084562,0.00002348496,0.00002830219,0.000002385497,0.000007921086,0.00005598353,0.000001584692,0.0003136056],"genre_scores_gemma":[0.9995626,0.0001104386,0.00009700951,0.00003596074,0.000004880711,0.00000924731,0.00007655714,0.000001129454,0.0001020877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003866418,"threshold_uncertainty_score":0.007687807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004590197695708283,"score_gpt":0.2143922775556601,"score_spread":0.2098020798599518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}