{"id":"W2001761745","doi":"10.1016/s0049-3848(00)00240-1","title":"Responses to Aggregating Agents after Cleavage of GPIb of Human Platelets by the O-Sialoglycoprotein Endoprotease from Pasteurella haemolytica— Potential Surrogates for Bernard-Soulier Platelets?☆","year":2000,"lang":"en","type":"article","venue":"Thrombosis Research","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; McMaster University","funders":"Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Platelet; Ristocetin; Disintegrin; Glycoprotein Ib; Chemistry; Thrombin; Serotonin; Platelet Glycoprotein GPIb-IX Complex; Biochemistry; Von Willebrand factor; Glycoprotein; Platelet membrane glycoprotein; Receptor; Metalloproteinase; Internal medicine; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001029918,0.0003351735,0.0008644912,0.0002465354,0.0003470739,0.00005311005,0.0004300866,0.000220269,0.00179932],"category_scores_gemma":[0.0003868658,0.0002458085,0.000274441,0.000469345,0.0004709322,0.00009805313,0.0001631584,0.0004481876,0.0001199601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009238938,"about_ca_system_score_gemma":0.0001139202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002931942,"about_ca_topic_score_gemma":0.0001026496,"domain_scores_codex":[0.9960978,0.000418937,0.0007248991,0.0006365353,0.001255691,0.0008661096],"domain_scores_gemma":[0.9977611,0.0006732147,0.000157869,0.0008018396,0.0002972663,0.0003087515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02575338,0.005302235,0.01989499,0.0005833195,0.002605166,0.00120655,0.005331314,0.00003076956,0.8261743,0.00006033792,0.03127486,0.08178284],"study_design_scores_gemma":[0.01056098,0.004364292,0.05431022,0.00109734,0.0003463117,0.00006344846,0.0007782434,0.0003005495,0.9229143,0.001186228,0.003585826,0.0004922696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927743,0.0004912564,0.00001758834,0.001360917,0.00004146219,0.003168956,0.0007446769,0.00003252012,0.001368309],"genre_scores_gemma":[0.9959214,0.0001719098,0.0005149393,0.0001241375,0.0001003451,0.0004407834,0.0001729775,0.00008334649,0.002470137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09674004,"threshold_uncertainty_score":0.9999994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07021631518099003,"score_gpt":0.3898424661829002,"score_spread":0.3196261510019102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}