{"id":"W2001874106","doi":"10.4161/pri.28939","title":"Lipopolysaccharide induced conversion of recombinant prion protein","year":2014,"lang":"en","type":"article","venue":"Prion","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"Alberta Prion Research Institute; Directorate for Biological Sciences","keywords":"Recombinant DNA; Gene isoform; Lipopolysaccharide; Guanidine; Chemistry; Proteinase K; Biochemistry; Cofactor; Endogeny; Bacterial outer membrane; Peptide; Cell biology; Biophysics; Enzyme; Escherichia coli; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002520971,0.0003639488,0.0001919487,0.0001866704,0.00007059193,0.0002155771,0.0001367475,0.000265134,0.001042247],"category_scores_gemma":[0.0002458038,0.0001049815,0.0002948683,0.0001313383,0.0001754904,0.0001611999,0.0002387936,0.000602612,0.0003210788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001677642,"about_ca_system_score_gemma":0.0001234912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000253349,"about_ca_topic_score_gemma":0.000227859,"domain_scores_codex":[0.9998308,0.0000437037,0.00002075222,0.00002355274,0.00004092745,0.00004020847],"domain_scores_gemma":[0.9997597,0.00007761936,0.00006344237,0.00003558665,0.00002683774,0.00003686411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000479532,0.00003616844,0.00003717361,0.00002278723,0.000003027214,0.00004777682,0.00000841586,0.00002031853,0.9994993,0.00003683325,0.00001118519,0.0002292074],"study_design_scores_gemma":[0.00001274392,0.0003444128,0.001014972,0.000006362462,0.000006728359,0.0001546304,0.00001188252,0.0004019448,0.9974935,0.00004117793,0.0005078597,0.000003832687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956608,0.0009596223,0.002077494,0.0000432963,0.00003872914,0.00003758543,0.0002472698,0.00005978646,0.0008753992],"genre_scores_gemma":[0.9938728,0.0005023133,0.002664392,0.00004985405,0.000009269067,0.00003636022,0.0008615527,0.00002293558,0.001980584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042247,"threshold_uncertainty_score":0.003486633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008572292790331603,"score_gpt":0.2304963219618097,"score_spread":0.221924029171478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}