{"id":"W2001874106","doi":"10.4161/pri.28939","title":"Lipopolysaccharide induced conversion of recombinant prion protein","year":2014,"lang":"en","type":"article","venue":"Prion","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"Alberta Prion Research Institute; Directorate for Biological Sciences","keywords":"Recombinant DNA; Gene isoform; Lipopolysaccharide; Guanidine; Chemistry; Proteinase K; Biochemistry; Cofactor; Endogeny; Bacterial outer membrane; Peptide; Cell biology; Biophysics; Enzyme; Escherichia coli; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002610639,0.0001020628,0.0001172025,0.00003750745,0.0000535399,0.00001010872,0.0001439949,0.0001179851,0.00003049607],"category_scores_gemma":[0.0001541899,0.00009562747,0.00008060302,0.00004413528,0.00002288468,0.000004766257,0.0001125922,0.00006132374,0.00001402635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001096866,"about_ca_system_score_gemma":0.00004000608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004340589,"about_ca_topic_score_gemma":0.000002590729,"domain_scores_codex":[0.9992369,0.00007682566,0.000182869,0.0002322926,0.0001190468,0.0001520819],"domain_scores_gemma":[0.9994454,0.000006366026,0.0001323135,0.0002836525,0.00006068155,0.00007158408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009756919,0.00004074227,0.0006133388,0.00005494133,0.000009992983,1.918518e-7,0.00001378802,0.000001993798,0.9350868,0.0002634144,0.0001557083,0.06366149],"study_design_scores_gemma":[0.000490235,0.0003655776,0.001198628,0.00005815092,0.000009916452,0.000001679189,0.00001174505,0.0001533137,0.9730743,0.0002598669,0.02424856,0.0001280078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968704,0.0007803144,0.001552315,0.0001097026,0.0001815716,0.0002954177,0.000001440049,0.00001382989,0.0001950312],"genre_scores_gemma":[0.9987476,0.0003529502,0.0005685779,0.00007377618,0.00008980259,0.00001833993,0.00002825784,0.00001408289,0.0001066428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06353348,"threshold_uncertainty_score":0.3899575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008572292790331603,"score_gpt":0.2304963219618097,"score_spread":0.221924029171478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}