{"id":"W2001925834","doi":"10.1016/j.mvr.2014.06.008","title":"Oxidative stress modulates nucleobase transport in microvascular endothelial cells","year":2014,"lang":"en","type":"article","venue":"Microvascular Research","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Western University","funders":"Canadian Institutes of Health Research; Schulich School of Medicine and Dentistry, Western University; University of Alberta; Faculty of Medicine and Dentistry, University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Peroxynitrite; Extracellular; Oxidative stress; Hypoxanthine; Chemistry; Adenosine; Biochemistry; Reactive oxygen species; Superoxide; Intracellular; Superoxide dismutase; Cell biology; Nucleoside transporter; Nucleoside; Endothelial stem cell; Pharmacology; Biology; Transporter; In vitro; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978751,0.0002107098,0.0002294678,0.0001713072,0.0002834722,0.0005376434,0.0002757782,0.0005293536,0.001318011],"category_scores_gemma":[0.000251623,0.0001561318,0.0002276026,0.0002104014,0.0001594912,0.000692288,0.0001932987,0.0005823108,0.0002105451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000365398,"about_ca_system_score_gemma":0.0001571992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009121421,"about_ca_topic_score_gemma":0.001143279,"domain_scores_codex":[0.9998521,0.00003504041,0.00001193003,0.00003370481,0.00002612736,0.00004114352],"domain_scores_gemma":[0.9998772,0.00003186559,0.00003027748,0.00001737161,0.0000203511,0.00002282523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007580161,0.00005123609,0.0004212719,0.0000492883,0.00001383334,0.00009205018,0.00005202676,0.0000469984,0.9956551,0.000332576,0.00006511704,0.00246259],"study_design_scores_gemma":[0.00004181517,0.000667115,0.01342385,0.00001257264,0.00004519741,0.0002439929,0.0001651302,0.001142734,0.9822871,0.0003375436,0.001623028,0.000009900538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930097,0.003769589,0.001646249,0.000277212,0.00007833522,0.00001046417,0.0001466273,0.00002292983,0.001038893],"genre_scores_gemma":[0.9966096,0.001594577,0.0005895263,0.00006903311,0.00002871105,0.00001102304,0.0001133412,0.000006680242,0.0009775158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001318011,"threshold_uncertainty_score":0.004409194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783981771032086,"score_gpt":0.2835095362625928,"score_spread":0.2656697185522719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}