{"id":"W2001958389","doi":"10.1016/j.clim.2010.03.334","title":"Toll-like Receptor 9 Expression on Hematopoietic-derived Cells is Required for the Enhancement of Cytotoxic T Lymphocyte Priming by Topical CpG Oligodeoxynucleotides","year":2010,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cytotoxic T cell; Priming (agriculture); CpG Oligodeoxynucleotide; Haematopoiesis; Toll-like receptor; Immunology; CpG site; Toll-Like Receptor 9; Receptor; Chemistry; Biology; Cancer research; Immune system; Cell biology; Innate immune system; Gene expression; Gene; Stem cell; In vitro; Biochemistry; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003051078,0.0001830441,0.0003246885,0.00002052421,0.000106711,0.00001445706,0.0004915477,0.0004471926,0.000202881],"category_scores_gemma":[0.0002260268,0.0001313658,0.0002627007,0.00002876352,0.0004100063,0.000005025865,0.0002141462,0.0002208518,0.00004386691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001019351,"about_ca_system_score_gemma":0.00007160949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006754467,"about_ca_topic_score_gemma":0.00000417852,"domain_scores_codex":[0.9984277,0.00009722511,0.0006328159,0.0004576174,0.0000937059,0.0002909167],"domain_scores_gemma":[0.9985991,0.0002882893,0.0002376032,0.0007132828,0.0001061316,0.00005560579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007667338,0.0002172742,0.00007302921,0.00001147333,0.0001245364,4.127688e-7,0.00005308795,6.763337e-7,0.9788564,0.00004410661,0.01409559,0.005756667],"study_design_scores_gemma":[0.0009733654,0.001500503,0.0001372206,0.00003106851,0.00002895014,0.000002653702,0.00008733057,0.00002590721,0.947044,0.00006539894,0.04995967,0.0001439685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941275,0.0005531358,0.002612634,0.0005547761,0.001651026,0.0003582216,0.00002992005,0.000009539242,0.0001032107],"genre_scores_gemma":[0.9944918,0.001489571,0.001105717,0.001436955,0.0002464434,0.0001179739,0.00004521928,0.00002152513,0.001044801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03586408,"threshold_uncertainty_score":0.5356944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02648176516898297,"score_gpt":0.3144150944641936,"score_spread":0.2879333292952106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}