{"id":"W2001958389","doi":"10.1016/j.clim.2010.03.334","title":"Toll-like Receptor 9 Expression on Hematopoietic-derived Cells is Required for the Enhancement of Cytotoxic T Lymphocyte Priming by Topical CpG Oligodeoxynucleotides","year":2010,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cytotoxic T cell; Priming (agriculture); CpG Oligodeoxynucleotide; Haematopoiesis; Toll-like receptor; Immunology; CpG site; Toll-Like Receptor 9; Receptor; Chemistry; Biology; Cancer research; Immune system; Cell biology; Innate immune system; Gene expression; Gene; Stem cell; In vitro; Biochemistry; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002930399,0.0003229592,0.0003220095,0.0001839059,0.0001553283,0.0004065242,0.0001920137,0.0003152126,0.002184424],"category_scores_gemma":[0.0002329636,0.0002451787,0.000210757,0.000110414,0.0002688299,0.0001353733,0.0001919925,0.0009850007,0.0007494353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003145627,"about_ca_system_score_gemma":0.0003442933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002805879,"about_ca_topic_score_gemma":0.0005762044,"domain_scores_codex":[0.9996591,0.0000764335,0.00002902262,0.00004841425,0.00006965519,0.0001172887],"domain_scores_gemma":[0.9997538,0.00005457985,0.00008707964,0.00003230661,0.00001689506,0.00005531145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001452106,0.00002333516,0.00005747195,0.00001360313,0.000001146888,0.00003376125,0.000004726965,0.00001551758,0.9991354,0.00006000013,0.00002119465,0.0004886546],"study_design_scores_gemma":[0.0000305594,0.0002542369,0.001922229,0.000004657768,0.0000117371,0.0002483217,0.00001413123,0.000364451,0.9961401,0.00003956982,0.0009678515,0.000002176656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935964,0.001123057,0.00272228,0.0001366036,0.00005024738,0.00005699293,0.0001958752,0.0001315532,0.001986915],"genre_scores_gemma":[0.9957305,0.0003197481,0.001706877,0.00004274919,0.00001286349,0.00002875744,0.0002009574,0.00002359201,0.001933956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002184424,"threshold_uncertainty_score":0.007307589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02648176516898297,"score_gpt":0.3144150944641936,"score_spread":0.2879333292952106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}