{"id":"W2001991926","doi":"10.1111/j.1538-7836.2008.03012.x","title":"Severe protein S deficiency resulting from two novel mutations in PROS1 presenting with a relatively mild clinical phenotype","year":2008,"lang":"en","type":"letter","venue":"Journal of Thrombosis and Haemostasis","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Phenotype; Clinical phenotype; Medicine; Protein S deficiency; Mutation; Protein S; Internal medicine; Genetics; Biology; Protein C; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005245986,0.00427,0.001848491,0.001609336,0.001245676,0.001456453,0.001547309,0.009411567,0.003935555],"category_scores_gemma":[0.00481525,0.0007770534,0.001364788,0.001019001,0.002356888,0.001278801,0.001285864,0.003362067,0.001060443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009972668,"about_ca_system_score_gemma":0.0006411441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232032,"about_ca_topic_score_gemma":0.000814667,"domain_scores_codex":[0.9991682,0.0001858524,0.0001050774,0.0002118984,0.0001291234,0.0001999603],"domain_scores_gemma":[0.9967187,0.00169956,0.0005070794,0.0001715428,0.0001885338,0.0007144565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001694595,0.00002294203,0.001482209,0.00002516553,0.00001396632,0.9947231,0.00006960231,0.00004646619,0.001786048,0.0002872496,0.000753357,0.000620392],"study_design_scores_gemma":[0.0001352866,0.0002403774,0.006067628,0.0000130976,0.00004821258,0.9884575,0.0001109385,0.0007301712,0.001854693,0.0004680785,0.001841476,0.00003249933],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9436912,0.001661223,0.003843923,0.0234153,0.002326861,0.0002328636,0.0007218737,0.0004022805,0.02370442],"genre_scores_gemma":[0.9870265,0.0005325565,0.001859991,0.003022137,0.002423669,0.00004344235,0.0002558672,0.00007587884,0.00476007],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.009411567,"threshold_uncertainty_score":0.01316571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1437396256455896,"score_gpt":0.3650204861287694,"score_spread":0.2212808604831797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}