{"id":"W2002006497","doi":"10.1016/s0378-1097(03)00956-x","title":"Production of heterologous protein by<i>Methylobacterium extorquens</i>in high cell density fermentation","year":2004,"lang":"en","type":"article","venue":"FEMS Microbiology Letters","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Biotechnology Research Institute; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Heterologous; Methylobacterium; Fermentation; Chemistry; Yeast; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001751617,0.0001732982,0.0001950789,0.00007512129,0.00003270603,0.000005606066,0.0001105924,0.000182573,0.000003527459],"category_scores_gemma":[0.00002501901,0.00017358,0.00005691177,0.0001048653,0.0001214797,0.000006415388,0.00003859552,0.0001218885,0.000007074765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004327706,"about_ca_system_score_gemma":0.00001973441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001729038,"about_ca_topic_score_gemma":0.00002544351,"domain_scores_codex":[0.9989296,0.0000777097,0.0002673869,0.000443075,0.00003091183,0.0002513521],"domain_scores_gemma":[0.9995471,9.422398e-7,0.0001292291,0.0002548672,0.0000407774,0.00002709322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009357411,0.0001015867,0.0005920797,0.00002890059,0.0000181232,0.000001473087,0.00004302716,0.0006133469,0.9975026,0.000002713564,0.0008727197,0.0001298225],"study_design_scores_gemma":[0.0006460148,0.0001559773,0.003886459,0.00001461659,0.000009806082,0.00004083897,0.000009593461,1.450637e-7,0.9936088,0.000007354645,0.001456304,0.0001640471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969227,0.0001700735,0.0008200697,0.0009115817,0.000776594,0.0003531211,0.00002383679,0.00001870856,0.000003354266],"genre_scores_gemma":[0.9972658,0.00003233152,0.001447255,0.000364123,0.0002129848,0.00002200379,0.000516473,0.00001792621,0.0001211665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003893789,"threshold_uncertainty_score":0.7078387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002836837142007742,"score_gpt":0.1801947865807305,"score_spread":0.1773579494387227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}