{"id":"W2002030208","doi":"10.1016/j.cell.2011.10.017","title":"NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function","year":2011,"lang":"en","type":"article","venue":"Cell","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":264,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Howard Hughes Medical Institute; Health Science Center, University of Tennessee; Institute of Genetics; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; École Polytechnique Fédérale de Lausanne; Leona M. and Harry B. Helmsley Charitable Trust; University of Pennsylvania; University of California, Los Angeles; National Science Foundation; March of Dimes Foundation; Glenn Foundation for Medical Research","keywords":"Biology; Corepressor; Transcription factor; Mef2; Gene knockdown; Cell biology; Mitochondrion; Nuclear receptor co-repressor 1; Nuclear receptor; Skeletal muscle; Oxidative phosphorylation; NRF1; Mitochondrial biogenesis; Gene; Genetics; Biochemistry; Enhancer; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003645725,0.0000636288,0.0001743676,0.00002159914,0.00001538178,0.000001018527,0.00002185477,0.00005958967,0.0005448525],"category_scores_gemma":[0.0000133865,0.00004716479,0.00003398133,0.0000440727,0.0000715765,0.00002880521,0.00001586234,0.00005944952,0.00004042847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003229452,"about_ca_system_score_gemma":0.00001379843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003589961,"about_ca_topic_score_gemma":4.369054e-7,"domain_scores_codex":[0.9996182,0.0000178971,0.00009724924,0.0001264929,0.00005487293,0.00008532038],"domain_scores_gemma":[0.9997038,0.00001174978,0.00004758825,0.0001255838,0.00004421863,0.0000671098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001288418,0.0001065119,0.001368775,0.00004470227,0.00002327187,0.000005159235,0.0007215745,4.462956e-8,0.9950752,0.0001113311,0.001174018,0.001240575],"study_design_scores_gemma":[0.001188612,0.0004876972,0.4291161,0.00001858848,0.0001579418,0.000002614582,0.0002936903,0.00005123375,0.5609081,0.001079713,0.006619143,0.00007660921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933226,0.0006845034,0.0002396207,0.0000265219,0.00007072163,0.0001298364,0.000004279769,0.00001679692,0.005505145],"genre_scores_gemma":[0.9963386,0.00006518017,0.001068111,0.0003222563,0.00005075271,0.000004078723,0.000004662996,0.00000627785,0.002140055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4341671,"threshold_uncertainty_score":0.5965753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05072093662493626,"score_gpt":0.248711671636167,"score_spread":0.1979907350112308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}