{"id":"W2002030208","doi":"10.1016/j.cell.2011.10.017","title":"NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function","year":2011,"lang":"en","type":"article","venue":"Cell","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":264,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Howard Hughes Medical Institute; Health Science Center, University of Tennessee; Institute of Genetics; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; École Polytechnique Fédérale de Lausanne; Leona M. and Harry B. Helmsley Charitable Trust; University of Pennsylvania; University of California, Los Angeles; National Science Foundation; March of Dimes Foundation; Glenn Foundation for Medical Research","keywords":"Biology; Corepressor; Transcription factor; Mef2; Gene knockdown; Cell biology; Mitochondrion; Nuclear receptor co-repressor 1; Nuclear receptor; Skeletal muscle; Oxidative phosphorylation; NRF1; Mitochondrial biogenesis; Gene; Genetics; Biochemistry; Enhancer; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001947244,0.0003482661,0.0004003585,0.0002820916,0.0003245444,0.0005498716,0.0005011612,0.0003804274,0.00178285],"category_scores_gemma":[0.0002436697,0.0001116206,0.0002636553,0.0001748692,0.0003666712,0.0003092719,0.0002538362,0.0005476355,0.0004899321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005732554,"about_ca_system_score_gemma":0.000321702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001689096,"about_ca_topic_score_gemma":0.002407145,"domain_scores_codex":[0.9998456,0.00001272483,0.000008859994,0.00005352573,0.00004695477,0.00003226901],"domain_scores_gemma":[0.9998288,0.00001401813,0.00006362939,0.00001422097,0.00002728728,0.00005191734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004455441,0.00002406145,0.001383657,0.00005576003,0.0000199256,0.0002645784,0.00002086042,0.0001586861,0.9918542,0.0007825044,0.0002699638,0.004720258],"study_design_scores_gemma":[0.00009172131,0.000555046,0.07244673,0.0000416118,0.00009263025,0.003710461,0.0001810289,0.003899781,0.8953101,0.0006676321,0.02295195,0.00005137029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719819,0.01011486,0.008624895,0.0007934021,0.0002985025,0.0000480925,0.001202989,0.0002382517,0.006697128],"genre_scores_gemma":[0.9842122,0.002422945,0.00447664,0.0002249035,0.00007288801,0.00002412904,0.001717344,0.00004899648,0.006800052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00178285,"threshold_uncertainty_score":0.005964279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05072093662493626,"score_gpt":0.248711671636167,"score_spread":0.1979907350112308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}