{"id":"W2002030307","doi":"10.1016/j.bbrc.2006.04.064","title":"Ion dependence of ligand binding to metabotropic glutamate receptors","year":2006,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metabotropic glutamate receptor; Metabotropic glutamate receptor 1; Quisqualic acid; Metabotropic receptor; Chemistry; Metabotropic glutamate receptor 5; Divalent; Metabotropic glutamate receptor 2; Ligand (biochemistry); Receptor; Agonist; Biochemistry; Biophysics; Stereochemistry; Glutamate receptor; Biology; Kainic acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000389246,0.0002374953,0.0004065894,0.0002347964,0.0003475202,0.0006776674,0.0007624418,0.0003886568,0.005762394],"category_scores_gemma":[0.001751198,0.0002669486,0.0002405027,0.0002568884,0.0003598471,0.0007863779,0.0003218834,0.000686145,0.000914612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007375769,"about_ca_system_score_gemma":0.0002846403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001793743,"about_ca_topic_score_gemma":0.001837541,"domain_scores_codex":[0.9995466,0.00009267579,0.00004357634,0.00004676709,0.0001367477,0.000133486],"domain_scores_gemma":[0.9990035,0.0006233843,0.00007823698,0.00008029322,0.0001233301,0.00009128433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002505123,0.00004744116,0.0003225258,0.0001181562,0.00002097402,0.000146005,0.00009006134,0.0002991836,0.9927974,0.001069162,0.0002982574,0.002285757],"study_design_scores_gemma":[0.0001330598,0.0004069556,0.01309226,0.00002302315,0.00004053004,0.0008285067,0.00009967532,0.004416025,0.9765186,0.0005123724,0.003891275,0.00003782105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819353,0.003155291,0.002204927,0.0005228909,0.00008106734,0.0000311112,0.0006333984,0.0001192103,0.01131678],"genre_scores_gemma":[0.9950444,0.001317166,0.0006793816,0.0001595,0.00003608708,0.00002167619,0.0009079688,0.00005737264,0.0017766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005762394,"threshold_uncertainty_score":0.01927716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1258714333754098,"score_gpt":0.4141877284548595,"score_spread":0.2883162950794497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}