{"id":"W2002033363","doi":"10.1371/journal.ppat.1000100","title":"Genome-Wide Screen of Three Herpesviruses for Protein Subcellular Localization and Alteration of PML Nuclear Bodies","year":2008,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Genome Canada; Ontario Genomics; Canadian Institutes of Health Research; Canada Research Chairs; Ontario Genomics Institute","keywords":"Cajal body; Biology; Subcellular localization; Lytic cycle; Promyelocytic leukemia protein; Herpes simplex virus; Nucleolus; Cell biology; Nuclear localization sequence; Protein subcellular localization prediction; Virology; Genome; Nuclear pore; Nuclear protein; Virus; Cytoplasm; Gene; RNA; Genetics; Transcription factor; RNA splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003302021,0.0003253294,0.0004088376,0.0005068009,0.0003603364,0.000428176,0.0003360076,0.0004207663,0.0004618184],"category_scores_gemma":[0.0002910483,0.0002138461,0.000426821,0.0004839872,0.0002457668,0.0001317758,0.000320808,0.0005186215,0.000162311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003944114,"about_ca_system_score_gemma":0.0002563076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006347304,"about_ca_topic_score_gemma":0.001764915,"domain_scores_codex":[0.999767,0.00002900381,0.00001800245,0.0000590979,0.00008972267,0.00003711283],"domain_scores_gemma":[0.999795,0.00006643379,0.00004602985,0.0000272604,0.00002373792,0.00004152174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007168606,0.00002627312,0.001068862,0.00002572309,0.00001904647,0.00009189727,0.00001954718,0.00005417674,0.9969497,0.00004439109,0.0000333161,0.001595358],"study_design_scores_gemma":[0.0000511742,0.0005879399,0.04807538,0.0000165682,0.0002443936,0.002001059,0.0001370541,0.001572623,0.942188,0.0001466151,0.004958054,0.00002114773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933026,0.001507585,0.003277659,0.00007715799,0.00001578768,0.00006672247,0.0009402353,0.00006506376,0.000747263],"genre_scores_gemma":[0.9854228,0.001219647,0.007448327,0.0001541254,0.000007449787,0.00005927042,0.004407016,0.00005429983,0.001227124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006347304,"threshold_uncertainty_score":0.002861738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05611458069139576,"score_gpt":0.2717343185643398,"score_spread":0.215619737872944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}