{"id":"W2002087684","doi":"10.1371/journal.pone.0027209","title":"Substance P Is a Mechanoresponsive, Autocrine Regulator of Human Tenocyte Proliferation","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tendon Structure and Treatment","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Coastal Health; University of British Columbia","funders":"Canadian Institutes of Health Research; Svenska Läkaresällskapet; University of British Columbia; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Stiftelsen Forska Utan Djurförsök; Fondation pour la Recherche Médicale; Michael Smith Health Research BC; Kempe Foundation; Tore Nilsons Stiftelse för Medicinsk Forskning","keywords":"Tendinopathy; Tendon; Cell biology; Substance P; Tendinosis; Autocrine signalling; Cell growth; Cell culture; Cell; Biology; Immunology; Chemistry; Receptor; Medicine; Internal medicine; Anatomy; Neuropeptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003767659,0.0001075638,0.0002918826,0.00008213735,0.00003668247,0.000002436524,0.00004237917,0.00004607669,0.0004584987],"category_scores_gemma":[0.00001637765,0.00008439322,0.00004941567,0.0001105105,0.00003620214,0.00004622548,0.00001128339,0.00006464079,0.00002059907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003530553,"about_ca_system_score_gemma":0.00003448683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002390208,"about_ca_topic_score_gemma":0.00001652749,"domain_scores_codex":[0.9992079,0.00001636597,0.0002044633,0.0001776153,0.0002606709,0.0001330012],"domain_scores_gemma":[0.9993267,0.00000845521,0.00009170284,0.0003223695,0.0001774969,0.00007325567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001640827,0.003189924,0.07075337,0.0003658427,0.001254015,0.0001127925,0.005133735,3.214327e-8,0.9075957,0.008786086,0.0003561825,0.0008115295],"study_design_scores_gemma":[0.001360588,0.0007785428,0.1055229,0.0001490635,0.0003925182,0.00001069511,0.00002857297,0.00001189272,0.8901131,0.001531578,0.00003083098,0.00006975311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966282,0.0001637882,0.0000241697,0.0002569908,0.00001303564,0.0005431189,0.00001292696,0.00006238167,0.002295414],"genre_scores_gemma":[0.990801,0.00001572702,0.006020346,0.0001869093,0.00005316728,0.0000465917,0.00001643715,0.00001742634,0.002842338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03476952,"threshold_uncertainty_score":0.5020239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09442269647700657,"score_gpt":0.2626587009884049,"score_spread":0.1682360045113984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}