{"id":"W2002114667","doi":"10.1073/pnas.0911295107","title":"Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Broad Institute; National Institutes of Health; University of Houston; U.S. Department of Health and Human Services","keywords":"Biology; Genetics; Indel; Genome; Nonsynonymous substitution; Single-nucleotide polymorphism; Whole genome sequencing; Deep sequencing; Population; DNA sequencing; Genotype; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003604132,0.0001490896,0.0003145951,0.0007158591,0.0004722945,0.0006580634,0.0002539256,0.0002599405,0.0003557371],"category_scores_gemma":[0.0009862558,0.0002186034,0.0002047896,0.0008388862,0.0007171938,0.0003303832,0.0004028793,0.0004316829,0.00006000197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002189127,"about_ca_system_score_gemma":0.0009990085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04745426,"about_ca_topic_score_gemma":0.06533663,"domain_scores_codex":[0.9998081,0.00002438381,0.000006609193,0.00005576281,0.00005452767,0.00005068597],"domain_scores_gemma":[0.999661,0.00009587476,0.00009816446,0.00003025973,0.00006204815,0.00005266415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003287349,0.00004331217,0.1813953,0.0001497949,0.0001448478,0.0003715747,0.001571409,0.005985356,0.7739824,0.002784195,0.0003332485,0.03290967],"study_design_scores_gemma":[0.000004508518,0.00004471776,0.9823148,0.00000990538,0.0000413877,0.0001997705,0.0005353412,0.008171619,0.005708296,0.001357181,0.001597914,0.00001443571],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954876,0.0003750565,0.002809161,0.00007413174,0.000002006038,0.00000931071,0.0001972515,0.00002581599,0.001019675],"genre_scores_gemma":[0.9968421,0.0002479059,0.002242129,0.0000541011,0.000003545992,0.00001078835,0.0003986199,0.000008113497,0.0001926441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04745426,"threshold_uncertainty_score":0.09435612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08328351657648289,"score_gpt":0.3643643083009509,"score_spread":0.281080791724468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}