{"id":"W2002116074","doi":"10.1371/journal.pone.0075665","title":"Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":234,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; McKnight Foundation; Chinese Center for Disease Control and Prevention; York University; Emory University; Medical Research and Materiel Command; Office of Research and Development; Bill and Melinda Gates Foundation; U.S. Department of Veterans Affairs; Henry M. Jackson Foundation; School of Medicine, New York University; U.S. Department of Health and Human Services; U.S. Department of Defense","keywords":"Epitope; Vaccine trial; Virology; Antibody; Immunology; Vaccine efficacy; Biology; Neutralizing antibody; HIV vaccine; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000300222,0.00008402942,0.0002263325,0.0001109191,0.00005550832,0.000005585116,0.0001002325,0.00007666349,0.00003466393],"category_scores_gemma":[0.0002976689,0.00004212271,0.00002618481,0.0002294203,0.00006714215,0.00003740043,0.0000287766,0.0002683364,0.0001191648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001250524,"about_ca_system_score_gemma":0.00002939081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002079868,"about_ca_topic_score_gemma":0.0008527669,"domain_scores_codex":[0.9989761,0.0004640708,0.0002058114,0.0001326824,0.00005336064,0.0001679789],"domain_scores_gemma":[0.9990916,0.0005365052,0.00008284233,0.0002278457,0.00004692792,0.00001422593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.09683562,0.04172731,0.5197269,0.0002402318,0.004550467,0.00005164242,0.05108097,0.0002422176,0.2635312,0.0006042355,0.006587226,0.01482201],"study_design_scores_gemma":[0.05771652,0.00711885,0.9000475,0.0002984847,0.0002728584,0.00002199916,0.0005182291,0.00004167836,0.03319562,0.00008364772,0.000538796,0.000145775],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969758,0.0001784742,0.000005642431,0.001330122,0.00001920336,0.001361413,0.00002569345,0.000008528608,0.00009506946],"genre_scores_gemma":[0.9991867,0.0003636373,0.00007423901,0.00001883558,0.00001781912,0.0001708,0.00003099407,0.00000654722,0.0001304159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3803206,"threshold_uncertainty_score":0.3144152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02952524931452424,"score_gpt":0.2482398381105791,"score_spread":0.2187145887960548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}