{"id":"W2002116074","doi":"10.1371/journal.pone.0075665","title":"Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":234,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; McKnight Foundation; Chinese Center for Disease Control and Prevention; York University; Emory University; Medical Research and Materiel Command; Office of Research and Development; Bill and Melinda Gates Foundation; U.S. Department of Veterans Affairs; Henry M. Jackson Foundation; School of Medicine, New York University; U.S. Department of Health and Human Services; U.S. Department of Defense","keywords":"Epitope; Vaccine trial; Virology; Antibody; Immunology; Vaccine efficacy; Biology; Neutralizing antibody; HIV vaccine; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002019963,0.0003127574,0.0004870366,0.0001476448,0.0001426084,0.0004249843,0.0001813339,0.0005804017,0.001094338],"category_scores_gemma":[0.002513623,0.0001602399,0.0003026873,0.0001239409,0.0002170443,0.0002299867,0.0001082087,0.0006183585,0.0001755068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001574595,"about_ca_system_score_gemma":0.000163983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002759121,"about_ca_topic_score_gemma":0.0002436086,"domain_scores_codex":[0.99922,0.0004323957,0.00004030119,0.00009102409,0.000130584,0.00008578692],"domain_scores_gemma":[0.9983904,0.000756887,0.0003988735,0.0001272835,0.0001140498,0.0002125208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03079634,0.001045579,0.8786598,0.0001211045,0.0008657202,0.0009018814,0.0003311956,0.0007162143,0.04784643,0.0002194445,0.001026084,0.03747021],"study_design_scores_gemma":[0.0005911669,0.01242259,0.9770722,0.00001950279,0.0003330297,0.001430642,0.00005130436,0.001175627,0.005776516,0.0001717762,0.0009447622,0.00001093781],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985216,0.00046882,0.0001904259,0.00005393173,0.000008806295,0.00001343588,0.00003623181,0.00001092733,0.0006958615],"genre_scores_gemma":[0.9996148,0.00003995361,0.00005326806,0.00002566491,0.00001333896,0.000003921225,0.00005107884,0.000002247203,0.0001956794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002019963,"threshold_uncertainty_score":0.0106827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02952524931452424,"score_gpt":0.2482398381105791,"score_spread":0.2187145887960548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}