{"id":"W2002257803","doi":"10.1038/mt.2014.116","title":"Induction of Androgen Formation in the Male by a TAT-VDAC1 Fusion Peptide Blocking 14-3-3ɛ Protein Adaptor and Mitochondrial VDAC1 Interactions","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Brown University","keywords":"Signal transducing adaptor protein; VDAC1; Blocking (statistics); Peptide; Biology; Cell biology; Fusion protein; Chemistry; Biochemistry; Signal transduction; Recombinant DNA; Computer science; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002008124,0.0003211394,0.0002319959,0.0003554201,0.0004627026,0.0003536031,0.0002840366,0.000305503,0.003849292],"category_scores_gemma":[0.0001078064,0.0002261522,0.0004322092,0.0001451522,0.0004000203,0.0001722244,0.0002590508,0.0009001524,0.000662717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003766858,"about_ca_system_score_gemma":0.0005012985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009652941,"about_ca_topic_score_gemma":0.002078013,"domain_scores_codex":[0.9997832,0.0000411642,0.00001201858,0.0000393209,0.00005652546,0.00006781522],"domain_scores_gemma":[0.9998206,0.00002521032,0.00002891635,0.00001893254,0.00001057493,0.00009562871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001608982,0.00003682123,0.0001210155,0.00001270846,0.000003821581,0.00008219441,0.00002089038,0.00003788658,0.9981939,0.0004551357,0.00006279046,0.0008119717],"study_design_scores_gemma":[0.00002052489,0.0003150703,0.003213699,0.000003557846,0.000008898522,0.0002517989,0.00003435104,0.000418641,0.992429,0.00008912972,0.003209983,0.000005492629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839202,0.002315809,0.005733651,0.0004873438,0.0002798688,0.0000527979,0.0005483894,0.00026316,0.006398715],"genre_scores_gemma":[0.9792093,0.0005844095,0.001691619,0.0001108741,0.0000367071,0.00002849835,0.0003661439,0.0000503084,0.01792222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003849292,"threshold_uncertainty_score":0.01287717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009184848074954746,"score_gpt":0.2451398387104622,"score_spread":0.2359549906355075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}