{"id":"W2002257803","doi":"10.1038/mt.2014.116","title":"Induction of Androgen Formation in the Male by a TAT-VDAC1 Fusion Peptide Blocking 14-3-3ɛ Protein Adaptor and Mitochondrial VDAC1 Interactions","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Brown University","keywords":"Signal transducing adaptor protein; VDAC1; Blocking (statistics); Peptide; Biology; Cell biology; Fusion protein; Chemistry; Biochemistry; Signal transduction; Recombinant DNA; Computer science; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002225764,0.0001676863,0.0001408144,0.00009291931,0.0001075447,0.00004532765,0.0001720486,0.0001230427,0.00002282419],"category_scores_gemma":[0.0000894326,0.0001405135,0.00008585008,0.0001376064,0.00006317341,0.00002821232,0.00004736309,0.0001874555,0.00000378997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002248277,"about_ca_system_score_gemma":0.00002387259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000101182,"about_ca_topic_score_gemma":0.00005684022,"domain_scores_codex":[0.9987688,0.0002954699,0.0002951309,0.0002769354,0.0001797297,0.0001839263],"domain_scores_gemma":[0.9993227,0.00001871359,0.0001808966,0.0003486031,0.00009099476,0.00003813628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001780002,0.0001030941,0.00005820143,0.00001081671,0.0000287801,0.000001793512,0.0002783573,0.00002740102,0.9923539,0.00008381468,0.0008140196,0.006061786],"study_design_scores_gemma":[0.001015719,0.0003792653,0.0001024323,0.00004896835,0.0000101147,0.0001203853,0.0002196463,0.000222839,0.9392013,0.0002054567,0.05831871,0.0001551919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832798,0.0005428364,0.01428143,0.000422912,0.0001219635,0.0007904944,0.00001527812,0.0000103437,0.0005349853],"genre_scores_gemma":[0.9976311,0.00009785533,0.001298754,0.0002214106,0.0001329881,0.000240908,0.0001165499,0.00002476482,0.0002356105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05750469,"threshold_uncertainty_score":0.5729973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009184848074954746,"score_gpt":0.2451398387104622,"score_spread":0.2359549906355075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}