{"id":"W2002289185","doi":"10.1002/pbc.21269","title":"Sickle cell disease caused by Hb S/Québec‐CHORI: Treatment with hydroxyurea and response","year":2007,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Blood cancer; Medicine; Transversion; Disease; Hemoglobinopathy; Hemoglobin; Genetics; Anemia; Fetal hemoglobin; Compound heterozygosity; Gene; Cancer; Pediatrics; Mutation; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397484,0.000304489,0.0002645865,0.0002253233,0.00110407,0.0002171815,0.0003256726,0.0009275639,0.001391907],"category_scores_gemma":[0.001031998,0.00009259359,0.0002191353,0.0002388975,0.0003128573,0.0001868941,0.0001954964,0.0008852299,0.0002428419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001451385,"about_ca_system_score_gemma":0.001321224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1349022,"about_ca_topic_score_gemma":0.203955,"domain_scores_codex":[0.9998873,0.0000180534,0.00000938617,0.00001937423,0.00002479678,0.0000410086],"domain_scores_gemma":[0.9994436,0.0001238016,0.00004643085,0.00001919336,0.00009492077,0.0002719672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001424967,0.00113771,0.1044264,0.0002608981,0.000160937,0.7508101,0.001984434,0.001384409,0.02310977,0.00124351,0.01541272,0.09864417],"study_design_scores_gemma":[0.0008000794,0.004273788,0.4070993,0.0002331079,0.000170912,0.5227279,0.001336537,0.005721999,0.009371573,0.001036246,0.04707745,0.0001510934],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9546916,0.00482747,0.002008095,0.007163543,0.0003814456,0.0004742212,0.0003372582,0.0001662823,0.02994998],"genre_scores_gemma":[0.9879541,0.0009255587,0.0007385041,0.002002353,0.0001142031,0.00004226456,0.000169976,0.00002278663,0.008030175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1349022,"threshold_uncertainty_score":0.268234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004674096323294806,"score_gpt":0.2269649851842727,"score_spread":0.2222908888609779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}