{"id":"W2002327264","doi":"10.1126/science.307.5709.515c","title":"The Ethics of Deriving Gametes from ES Cells","year":2005,"lang":"en","type":"letter","venue":"Science","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Context (archaeology); Somatic cell nuclear transfer; Somatic cell; Sperm; Neglect; Genetics; Embryo; Embryonic stem cell; Environmental ethics; Evolutionary biology; Gene; Psychology; Embryogenesis; Blastocyst; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008556842,0.0008318214,0.001941835,0.0007118614,0.006729106,0.006114183,0.002976181,0.1141017,0.004200765],"category_scores_gemma":[0.03972271,0.00129767,0.001769533,0.0006072451,0.008185768,0.004646526,0.003086972,0.08802806,0.003287281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007144297,"about_ca_system_score_gemma":0.006050586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00888131,"about_ca_topic_score_gemma":0.01393377,"domain_scores_codex":[0.9921104,0.002644159,0.0007489827,0.001114165,0.002205654,0.001176605],"domain_scores_gemma":[0.9791729,0.01495526,0.0009739114,0.000558047,0.002456878,0.001882866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005824077,0.00002055662,0.0002498652,0.00003595314,0.00002660201,0.0007535059,0.0002812133,0.00003948759,0.0001369811,0.006885047,0.9878957,0.003616764],"study_design_scores_gemma":[0.0001451093,0.00006302169,0.001083943,0.00031496,0.00007515509,0.001109846,0.0009329822,0.0002925775,0.0004461686,0.02391357,0.9715077,0.0001150611],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001785308,0.0008165164,0.00005607389,0.9872881,0.01070926,0.000004070394,0.00001261816,0.000006374875,0.0009285164],"genre_scores_gemma":[0.001784603,0.0002977804,0.00007892744,0.9857778,0.00823341,0.00001304902,0.000006020116,0.000008007427,0.003800495],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1141017,"threshold_uncertainty_score":0.05183578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02489145550217374,"score_gpt":0.303093573074721,"score_spread":0.2782021175725472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}