{"id":"W2002331449","doi":"10.1074/jbc.m401537200","title":"5-Oxo-6,8,11,14-eicosatetraenoic Acid Stimulates the Release of the Eosinophil Survival Factor Granulocyte/Macrophage Colony-stimulating Factor from Monocytes","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Christie (Canada); Merck Canada Inc. (Canada)","funders":"Division of Chemistry; National Institute of Diabetes and Digestive and Kidney Diseases; Heart and Stroke Foundation of Canada; National Heart, Lung, and Blood Institute; Heart And Stroke Foundation Of Quebec; National Institutes of Health; National Science Foundation","keywords":"Eosinophil; Leukotriene B4; Granulocyte; Monocyte; Chemotaxis; Cytokine; Immunology; Granulocyte macrophage colony-stimulating factor receptor; Eosinophilia; Granulocyte macrophage colony-stimulating factor; Chemistry; Macrophage; Eosinophil cationic protein; Leukotriene; Molecular biology; Biology; In vitro; Biochemistry; Macrophage colony-stimulating factor; Inflammation; Receptor; Asthma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002178923,0.0005204572,0.0004128021,0.0002916802,0.0001129471,0.0002947106,0.000101098,0.0002493388,0.00152719],"category_scores_gemma":[0.0001651947,0.000167913,0.0003217195,0.0001648504,0.0001878323,0.0001503925,0.0003096794,0.0004681975,0.0005871833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840753,"about_ca_system_score_gemma":0.000228332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004289525,"about_ca_topic_score_gemma":0.0007250859,"domain_scores_codex":[0.9997696,0.00005822334,0.00002573828,0.00002889635,0.0000520117,0.0000655281],"domain_scores_gemma":[0.9998631,0.000034225,0.00002112035,0.00001427241,0.0000156923,0.00005152044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002537232,0.00003587088,0.0001398825,0.00004842377,0.000003986764,0.00006250834,0.00001386724,0.00002514834,0.9982626,0.0000198686,0.0000279765,0.001106166],"study_design_scores_gemma":[0.0001089191,0.0009547512,0.0144255,0.00002555667,0.00002755243,0.0003016918,0.0000482838,0.0006475513,0.98097,0.00005574763,0.002425921,0.000008538381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914375,0.003839034,0.0022912,0.0001453464,0.00006082328,0.00005492191,0.0004420992,0.00005149163,0.001677542],"genre_scores_gemma":[0.9891146,0.002381381,0.004507025,0.0002348445,0.00007614517,0.00008284151,0.0009158873,0.00001804551,0.002669114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00152719,"threshold_uncertainty_score":0.005108953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03112878128896363,"score_gpt":0.2749358508186388,"score_spread":0.2438070695296752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}