{"id":"W2002369009","doi":"10.1021/bi0480178","title":"MAPK Modulates the DNA Binding of Adipocyte Enhancer-Binding Protein 1","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Dalhousie University","keywords":"Psychological repression; Chemistry; MAPK/ERK pathway; Repressor; Enhancer; Protein kinase A; Phosphorylation; DNA-binding domain; Binding site; DNA; Cell biology; Molecular biology; Transcription factor; Biochemistry; Biology; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008189956,0.0004142569,0.0001446304,0.0001319673,0.000161753,0.0001618426,0.0001228141,0.0001750957,0.002463738],"category_scores_gemma":[0.0001175701,0.0001484951,0.000160883,0.00007355941,0.0001569551,0.0001636175,0.0002275305,0.0003550055,0.00080415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000247272,"about_ca_system_score_gemma":0.0001211777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004228957,"about_ca_topic_score_gemma":0.0005472823,"domain_scores_codex":[0.999908,0.00002024686,0.000004430951,0.00002065261,0.00001820012,0.00002850357],"domain_scores_gemma":[0.9999453,0.000008395472,0.00001456796,0.000003949963,0.000009407344,0.00001842062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008533394,0.00001032145,0.00007498517,0.00001073228,0.000001006858,0.00001746875,0.000004881619,0.0000190188,0.9993387,0.00005503844,0.00001265057,0.0003699574],"study_design_scores_gemma":[0.00002180496,0.0001480972,0.008828228,0.000006450981,0.000009467753,0.0002110377,0.00002673628,0.001013979,0.9878224,0.0001572999,0.001750019,0.000004560401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941509,0.001457719,0.002147003,0.0001422884,0.00003581288,0.000009334653,0.0001867506,0.00005893834,0.001811229],"genre_scores_gemma":[0.9938915,0.000892418,0.001131941,0.00005198183,0.000009844874,0.00001524821,0.0002540945,0.00002127781,0.003731777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002463738,"threshold_uncertainty_score":0.008242011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007689251225057606,"score_gpt":0.2285722612468378,"score_spread":0.2208830100217802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}