{"id":"W2002440150","doi":"10.1038/ni958","title":"Enhanced T cell responses due to diacylglycerol kinase ζ deficiency","year":2003,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Diacylglycerol kinase; T-cell receptor; Cell biology; T cell; Lymphocytic choriomeningitis; Biology; Phosphatidic acid; Signal transduction; Ex vivo; Jurkat cells; Immune system; Protein kinase C; Immunology; CD8; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003693156,0.001508958,0.0006299251,0.0007420803,0.0002679331,0.0005914075,0.0005335117,0.0008539036,0.003125723],"category_scores_gemma":[0.000632067,0.0004397113,0.0004232506,0.0002953993,0.0009283287,0.0004533613,0.000504802,0.00174803,0.0009725944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004656714,"about_ca_system_score_gemma":0.0002734113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004758242,"about_ca_topic_score_gemma":0.0001892405,"domain_scores_codex":[0.9996124,0.00008839164,0.00007058145,0.00006560508,0.00006578049,0.00009728887],"domain_scores_gemma":[0.9993501,0.0001583245,0.0001430655,0.0001531889,0.00003789182,0.0001574135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002474175,0.0001143071,0.000707394,0.00009149775,0.00001563683,0.00136425,0.00002206023,0.0001245976,0.9931838,0.0002435219,0.000101211,0.001557611],"study_design_scores_gemma":[0.0006819841,0.00160032,0.01359546,0.00003092644,0.0001538946,0.008979228,0.0001256604,0.001281695,0.9704549,0.0007258232,0.002348109,0.00002212295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963599,0.0009153479,0.0009557061,0.0001586054,0.00007381093,0.00002992413,0.0002434819,0.0001050548,0.001158252],"genre_scores_gemma":[0.9973689,0.0004829949,0.0003837263,0.00006170154,0.00003400899,0.00002171404,0.0002124729,0.00002692984,0.001407593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003125723,"threshold_uncertainty_score":0.01045662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005312235269423049,"score_gpt":0.2364718050863162,"score_spread":0.2311595698168932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}