{"id":"W2002440150","doi":"10.1038/ni958","title":"Enhanced T cell responses due to diacylglycerol kinase ζ deficiency","year":2003,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Diacylglycerol kinase; T-cell receptor; Cell biology; T cell; Lymphocytic choriomeningitis; Biology; Phosphatidic acid; Signal transduction; Ex vivo; Jurkat cells; Immune system; Protein kinase C; Immunology; CD8; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002977297,0.0002871746,0.0003551178,0.0003642532,0.0003102664,0.00002169097,0.0003022915,0.00105214,0.00397193],"category_scores_gemma":[0.0008672783,0.0002648678,0.0001443471,0.0003824186,0.0001382928,0.0001284372,0.00007135218,0.001438656,0.007057547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001091006,"about_ca_system_score_gemma":0.0001066688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002622542,"about_ca_topic_score_gemma":0.000009084515,"domain_scores_codex":[0.9978406,0.0006258553,0.0003749985,0.0005077121,0.00004574225,0.0006051157],"domain_scores_gemma":[0.9987795,0.0003011866,0.0001341691,0.0005703673,0.0001846501,0.00003014249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001041582,0.0002258505,0.00004839489,0.000006521955,0.00005051411,0.00001250108,0.0003233531,0.000004780125,0.9796187,0.003834689,0.01253444,0.00229865],"study_design_scores_gemma":[0.0009473915,0.0004319531,0.001506774,0.000009309238,0.00001793117,0.0001762448,0.0003052261,1.854275e-7,0.6572083,0.00007551127,0.3391134,0.0002077844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9066914,0.01926098,0.001841924,0.0005712156,0.01793715,0.0004681826,0.000008101685,0.0002401904,0.05298083],"genre_scores_gemma":[0.9578074,0.0001046307,0.0001472931,0.001721257,0.00002613981,0.00006020162,0.00004873092,0.00002975309,0.04005466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.326579,"threshold_uncertainty_score":0.9999803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005312235269423049,"score_gpt":0.2364718050863162,"score_spread":0.2311595698168932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}