{"id":"W2002455191","doi":"10.1016/j.bbadis.2012.12.008","title":"Involvement of kinase PKC-zeta in the p62/p62P392L-driven activation of NF-κB in human osteoclasts","year":2012,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"NF-κB; Protein kinase C; Cell biology; Chemistry; Kinase; NFKB1; Signal transduction; Biology; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002477846,0.00025413,0.0001821136,0.0003232984,0.0002914081,0.0004016135,0.0001536893,0.000273057,0.001555709],"category_scores_gemma":[0.0002369916,0.000193306,0.0002992013,0.0001714368,0.000270132,0.0003459986,0.0003284173,0.0004355712,0.0007030449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004348845,"about_ca_system_score_gemma":0.0003485343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005493567,"about_ca_topic_score_gemma":0.0003805618,"domain_scores_codex":[0.9998885,0.00001904499,0.00001443551,0.00002025446,0.00002499394,0.00003267961],"domain_scores_gemma":[0.9999223,0.000007894724,0.00002251515,0.00001462044,0.00001245268,0.00002023278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001532899,0.00006466496,0.002060075,0.0001693365,0.00001574117,0.000580093,0.0000676393,0.0001242561,0.992391,0.0005300952,0.00008747251,0.002376756],"study_design_scores_gemma":[0.0004827439,0.0003343248,0.03942247,0.00003513073,0.00008100078,0.003073146,0.0002614904,0.002301448,0.9487798,0.001074398,0.004134019,0.00002010574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993201,0.003551174,0.001826447,0.0002182469,0.00003474268,0.00003298223,0.000423104,0.00002604649,0.0006864142],"genre_scores_gemma":[0.9977197,0.0008087022,0.0004711814,0.00002284967,0.000010483,0.00002568428,0.0002243623,0.000003956838,0.0007130547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001555709,"threshold_uncertainty_score":0.00520438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01272858672241132,"score_gpt":0.2624385282968186,"score_spread":0.2497099415744073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}