{"id":"W2002489327","doi":"10.1186/1742-4690-6-42","title":"TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+T cells","year":2009,"lang":"en","type":"article","venue":"Retrovirology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"Canadian Institutes of Health Research; Faculté de Médecine, Université Laval; Université Laval","keywords":"TLR2; TLR4; Immunology; Virus; Innate immune system; Toll-like receptor; Virology; TLR7; Viral entry; Transmission (telecommunications); Biology; Immune system; Interferon; Viral replication","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700133,0.0002014533,0.0004469022,0.0002660809,0.0001465921,0.00001396413,0.00006400904,0.0002497594,0.00002344267],"category_scores_gemma":[0.00004382181,0.0001810421,0.00004059489,0.000124992,0.0001083772,0.00008874919,0.00002463093,0.0002066746,0.0000318959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003824293,"about_ca_system_score_gemma":0.00001993648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001254965,"about_ca_topic_score_gemma":0.00007400359,"domain_scores_codex":[0.9986739,0.0002714495,0.0003267627,0.0003209136,0.00003664808,0.0003702836],"domain_scores_gemma":[0.9994882,0.000190979,0.00004719535,0.0001759089,0.00004725517,0.00005049808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009235066,0.0000450957,0.001087571,0.00005954085,0.00005274403,0.0000151926,0.0006095897,0.00002862055,0.9925948,0.0002323314,0.00006401882,0.004287017],"study_design_scores_gemma":[0.00166673,0.003599158,0.06159057,0.00009171193,0.00007730127,0.00009780702,0.00001820205,0.000004455535,0.9316394,0.00002118338,0.001011478,0.0001820377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968208,0.0005177229,0.0016307,0.0001683863,0.0001666039,0.0005270979,0.000005009613,0.00004413989,0.0001195476],"genre_scores_gemma":[0.9993216,0.00009618648,0.00006585856,0.0002719947,0.00002304423,0.00001834089,0.00001175718,0.00001524241,0.0001759225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06095541,"threshold_uncertainty_score":0.7382682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005498895127066794,"score_gpt":0.2125396711896747,"score_spread":0.2070407760626079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}