{"id":"W2002489327","doi":"10.1186/1742-4690-6-42","title":"TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+T cells","year":2009,"lang":"en","type":"article","venue":"Retrovirology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"Canadian Institutes of Health Research; Faculté de Médecine, Université Laval; Université Laval","keywords":"TLR2; TLR4; Immunology; Virus; Innate immune system; Toll-like receptor; Virology; TLR7; Viral entry; Transmission (telecommunications); Biology; Immune system; Interferon; Viral replication","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003583595,0.0004218099,0.0003034041,0.0002397826,0.0001705202,0.0005454219,0.0002244457,0.0005526801,0.003569544],"category_scores_gemma":[0.00040535,0.0001827506,0.0003669782,0.0001650804,0.0002216794,0.0003279677,0.000381343,0.0005653102,0.0007593127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002226045,"about_ca_system_score_gemma":0.0001607462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001053497,"about_ca_topic_score_gemma":0.0001044554,"domain_scores_codex":[0.999607,0.0001156567,0.00003765408,0.00004248268,0.00005220159,0.0001449972],"domain_scores_gemma":[0.9997491,0.0001089702,0.00003059752,0.00003404031,0.0000251654,0.00005205569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001166373,0.0001015534,0.0004507035,0.0001281213,0.000008576736,0.0001384367,0.00002885432,0.0001044041,0.9947155,0.0001934299,0.00004008999,0.002923996],"study_design_scores_gemma":[0.00006489502,0.001264555,0.004484425,0.00001431388,0.00002718388,0.0006591165,0.00005796037,0.000506828,0.9911641,0.0001281854,0.001621079,0.000007432035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939532,0.00222501,0.0008772395,0.00005887416,0.0000488763,0.00003981209,0.0001418256,0.00002260796,0.002632533],"genre_scores_gemma":[0.9951013,0.001090522,0.001398907,0.0000907128,0.00006221996,0.00008838491,0.0003266245,0.00001234717,0.001828958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003569544,"threshold_uncertainty_score":0.01194131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005498895127066794,"score_gpt":0.2125396711896747,"score_spread":0.2070407760626079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}