{"id":"W2002496559","doi":"10.1186/1471-2105-13-s3-s6","title":"Detection of gene expression changes at chromosomal rearrangement breakpoints in evolution","year":2012,"lang":"en","type":"article","venue":"BMC Bioinformatics","topic":"Genome Rearrangement Algorithms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Breakpoint; Biology; Genetics; Gene; Genome; Gene duplication; Chromosomal rearrangement; Chromosome; Computational biology; Karyotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000591723,0.0001903496,0.0003675522,0.001457863,0.0002865324,0.0005825848,0.000308175,0.0005603996,0.001745629],"category_scores_gemma":[0.002853412,0.0001373794,0.0003090723,0.001441306,0.0004811927,0.0003406703,0.0004366764,0.0005065053,0.0003410252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004282176,"about_ca_system_score_gemma":0.000159087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001205723,"about_ca_topic_score_gemma":0.001574191,"domain_scores_codex":[0.9995319,0.00007388974,0.0000262994,0.000229399,0.00007908349,0.00005937444],"domain_scores_gemma":[0.9981936,0.001049835,0.0003847852,0.0001156469,0.000149446,0.0001066722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001320404,0.0000959194,0.5498107,0.0005249638,0.0003666656,0.0004185849,0.0005931525,0.006820493,0.3833455,0.001134806,0.0003731723,0.05519554],"study_design_scores_gemma":[0.00002432813,0.0001905844,0.9515125,0.00002313882,0.0001093025,0.00089574,0.0002320628,0.010684,0.0329448,0.001591448,0.001771053,0.00002102382],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902562,0.0006656427,0.007749649,0.00007088402,0.000006217354,0.000008517086,0.0006230448,0.0001018884,0.0005180299],"genre_scores_gemma":[0.9904612,0.0002059783,0.007239716,0.00004122599,0.000009572007,0.00001777737,0.001749137,0.00002955892,0.0002458644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001745629,"threshold_uncertainty_score":0.005839765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362699507431398,"score_gpt":0.2269050628505561,"score_spread":0.2132780677762421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}