{"id":"W2002533513","doi":"10.1038/nsmb1340","title":"L3MBTL1 recognition of mono- and dimethylated histones","year":2007,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":false,"ca_institutions":"Structural Genomics Consortium; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Wellcome Trust; Genome Canada","keywords":"Histone; Chromatin; Histone H1; Chemistry; Histone code; Histone H2A; Nucleosome; Histone methyltransferase; Histone methylation; Methylation; Histone octamer; Lysine; Biochemistry; Cell biology; DNA; Biology; DNA methylation; Amino acid; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003100176,0.0002338668,0.0002574135,0.0002000726,0.0003609123,0.0006234055,0.0005395884,0.000378678,0.005419191],"category_scores_gemma":[0.0004458024,0.0002396791,0.0003070637,0.0001171001,0.0003244646,0.0003283203,0.0005910139,0.0006319844,0.001690733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000904992,"about_ca_system_score_gemma":0.0002179422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002394174,"about_ca_topic_score_gemma":0.003366293,"domain_scores_codex":[0.9997327,0.00002638957,0.00001049243,0.00006591753,0.00006413431,0.0001004202],"domain_scores_gemma":[0.999805,0.00003622555,0.00002988601,0.00002529554,0.00002928327,0.00007418236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002795092,0.0000115141,0.0005753925,0.00002349829,0.000004550288,0.00003821398,0.00002796957,0.00006935367,0.9971,0.0002963678,0.0002138885,0.001359744],"study_design_scores_gemma":[0.00001711431,0.00003621455,0.004860341,0.000005582674,0.000005104681,0.0001627423,0.00005762885,0.001712425,0.9911036,0.00009608165,0.001935235,0.00000785831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939866,0.0006858865,0.0027223,0.0002058329,0.00003942682,0.000006536361,0.0001980767,0.0001492882,0.002005946],"genre_scores_gemma":[0.9945327,0.0000826552,0.001102562,0.00009804415,0.000009297326,0.000008974152,0.0005756505,0.00003907916,0.003551178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005419191,"threshold_uncertainty_score":0.01812899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003062007461921618,"score_gpt":0.26335694997034,"score_spread":0.2602949425084184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}