{"id":"W2002533513","doi":"10.1038/nsmb1340","title":"L3MBTL1 recognition of mono- and dimethylated histones","year":2007,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":false,"ca_institutions":"Structural Genomics Consortium; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Wellcome Trust; Genome Canada","keywords":"Histone; Chromatin; Histone H1; Chemistry; Histone code; Histone H2A; Nucleosome; Histone methyltransferase; Histone methylation; Methylation; Histone octamer; Lysine; Biochemistry; Cell biology; DNA; Biology; DNA methylation; Amino acid; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001631361,0.0001796391,0.0001957277,0.00007337106,0.0000478613,0.000006158788,0.0001411607,0.000669702,0.00001094217],"category_scores_gemma":[0.00008978375,0.0001605447,0.00008144456,0.0000910673,0.0001652435,0.000002185666,0.0001044474,0.0002320616,9.267529e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001332188,"about_ca_system_score_gemma":0.00002432218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002532123,"about_ca_topic_score_gemma":0.00002220964,"domain_scores_codex":[0.9990491,0.00004918812,0.0002573494,0.0003399712,0.00006027659,0.0002441124],"domain_scores_gemma":[0.9994193,0.00001174747,0.0001467642,0.0002264538,0.0001270732,0.00006862004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008004396,0.000005866078,0.001119614,0.00001495793,0.00005845414,0.000004461498,0.0000187922,0.00000482426,0.9840958,0.0009961288,0.00002686935,0.0135742],"study_design_scores_gemma":[0.000677315,0.000417889,0.01743958,0.000009246522,0.00004228183,0.0001088638,0.00003935004,0.0001082781,0.9698859,0.008466932,0.002475431,0.0003288905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922391,0.004094899,0.002817298,0.00008704037,0.000262537,0.0001398264,0.00004845452,0.00001044719,0.0003004583],"genre_scores_gemma":[0.9922466,0.00009816015,0.006720901,0.0002695804,0.00007258919,0.000002041333,0.0005378209,0.00001982997,0.00003252776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01631997,"threshold_uncertainty_score":0.6546824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003062007461921618,"score_gpt":0.26335694997034,"score_spread":0.2602949425084184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}